Ep. 22: Novel Enhancers Featuring Dr. Paul Tesar

Jul 8, 2014

Dr. Paul Tesar, an assistant professor at Case Western Reserve University, shares his insights on pluripotent stem cells and enhancer activity. He discusses groundbreaking research, including how stem cell transplants can reverse sickle cell anemia and the role of gut bacteria in transplant success. Tesar also elaborates on the distinctions between naive and primed stem cells, crucial for understanding pluripotency. With a humorous take on life outside the lab, he highlights the balance needed for a fulfilling scientific career.

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Intro

00:00 • 2min

Breakthroughs in Stem Cell Research

02:22 • 16min

Exploring the Gut Microbiome and Cancer's Persistent Challenge

18:49 • 4min

Advancements in Genome Editing and Stem Cell Research

22:46 • 17min

The Role of Enhancers in Stem Cell Regulation

40:05 • 23min

Finding Balance: The Importance of Life Beyond the Lab

01:02:46 • 4min

The Secrecy Dilemma in Science

01:06:46 • 7min

Guest: This episode presents Dr. Paul Tesar from Case Western Reserve University. Dr Tesar talks about his paper in Cell Stem Cell. Resources and Links Bone Marrow Transplant Could Reverse Sickle Cell In Adults Freezing Testicle Tissue in Mice Offers Fertility Hope for Cancer Survivors Alzheimer's Linked to Brain Hyperactivity Obesity Linked To Type 2 Diabetes by an Absent Protein New Diabetes Drug Could Retrain GI Cells To Produce Insulin By Switching Off One Gene Not All Stem Cells Created Equal STAP Retracted Supermassive Black Hole Obscures Heart of Galaxy with 'Rare and Powerful Stream of Gas' Virus Kills Triple Negative Breast Cancer Cells, Tumor Cells in Mice Torsina Hypofunction Causes Abnormal Twisting Movements and Sensorimotor Circuit Neurodegeneration Destroying Bacterial Cell Walls May End Antibiotic Resistance Forever If Blocked Endocannabinoids Trigger Dementia Symptoms, Could Cannabis Prevent Alzheimer’s? Minimal Toolkit for Stem Cell Self-Renewal Dinosaurs Were Mesothermic Beasts, Neither Warm-Blooded Nor Cold-Blooded Geron hESC Trial to Resume? Stem Cells Form Light-Sensitive 3-D Retinal Tissue Delivering Capsules of Stem Cells Helps Repair Injured Bones Study Identifies Link Between Gut Bacteria Post SCT Survival Stem Cells Slow Retinal Degeneration in Dry AMD Clinical Trial Sustained ERK Activation Underlies Reprogramming in Regeneration-Competent Salamander Cells and Distinguishes Them from Their Mammalian Counterparts Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells Epigenomic Comparison Reveals Activation of “Seed” Enhancers during Transition from Naive to Primed Pluripotency Photo Reference: Courtesy of Dr. Paul Tesar Subscribe to our newsletter! Never miss updates about new episodes. Subscribe