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The Stem Cell Podcast

Ep. 22: Novel Enhancers Featuring Dr. Paul Tesar

Jul 8, 2014
Dr. Paul Tesar, an assistant professor at Case Western Reserve University, shares his insights on pluripotent stem cells and enhancer activity. He discusses groundbreaking research, including how stem cell transplants can reverse sickle cell anemia and the role of gut bacteria in transplant success. Tesar also elaborates on the distinctions between naive and primed stem cells, crucial for understanding pluripotency. With a humorous take on life outside the lab, he highlights the balance needed for a fulfilling scientific career.
01:14:52

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Dr. Paul Tesar explains how naive enhancers are crucial for regulating pluripotency in stem cells and their epigenetic differences.
  • Recent studies highlight the significant role of stem cells in treating conditions like sickle cell anemia and multiple sclerosis.

Deep dives

Overview of the Episode

The episode introduces the topic of naive enhancers, relating to a recent paper by Dr. Paul Tizar. The hosts, Dr. Christopher Pissano and Dr. Yosef Gannett, kick off the discussion by acknowledging the intriguing title and its implications in stem cell research. They emphasize the importance of staying engaged with their audience by encouraging feedback from previous episodes and mentioning the success from the ISSCR conference. The episode sets a lively tone, focusing on current developments in stem cell science.

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