Dr. Paul Tesar, an assistant professor at Case Western Reserve University, shares his insights on pluripotent stem cells and enhancer activity. He discusses groundbreaking research, including how stem cell transplants can reverse sickle cell anemia and the role of gut bacteria in transplant success. Tesar also elaborates on the distinctions between naive and primed stem cells, crucial for understanding pluripotency. With a humorous take on life outside the lab, he highlights the balance needed for a fulfilling scientific career.