Luke Cook, actor, comedian, content creator, and health science enthusiast, talks about ethics in healthcare, the influence of dietitians, the inconsistency of food labels, the junk food industry, the American food environment, traveling with kids, melatonin as a sleep aid, influencer dietitians, the effect of carotenoids on attractiveness, personal fitness journeys, fresh liquid whey, and whey protein consumption.

Dr. Mark Berhena discusses reducing dental plaque, receding gums, and optimal oral health. They cover mouthwash, fluoride controversy, root canals, and sleep apnea's impact on sleep quality. Topics include dental plaque, receding gums, and the oral microbiome. The importance of saturated fats for tooth and bone formation is emphasized. The potential damage caused by citrus on teeth and the pH levels of beverages is explored. Flossing benefits, recommended order for flossing and brushing, and functional dentistry risks are discussed. They also cover tracking sleep, mouth taping for better sleep, and the controversy of fluoride in toothpaste and water. Lastly, the significance of oral health for overall well-being and the role of nutrition are highlighted.

Renowned health and fitness expert, JJ Virgin, shares weight loss tips for women over 40, including the impact of muscle loss, prioritizing resistance training, and the role of stress hormones. They discuss the benefits of walking and debunk resistance training myths. They explore the fat-free trend, tracking calorie intake, and nutritional strategies. Coffee's effects on dopamine levels and hindrances to weight loss are covered. The role of red wine in health is mentioned, along with the drawbacks of ultra-processed foods. The importance of lifting to failure and intensity for women is highlighted.

Relationship expert Amy Chan discusses signs and mistakes leading to relationship failure, the importance of aligning actions and words in relationships, the danger of future tripping, and the impact of constant criticism. She also shares her personal journey to healing and highlights the lack of education on healthy relationships in schools.

Organizational psychologist and bestselling author, Benjamin Hardy, discusses regaining control and 10X-ing success, reflecting on growth and success, using a future goal as a filter, and challenges in adopting and having twins through IVF.

Guest Julia DiGangi, PhD, discusses the connection between emotions and personal empowerment, understanding and controlling emotions, the impact of trauma on emotions and relationships, breaking patterns, and gaining emotional control. They also explore the benefits of colostrum, coping with substances and emotional pain, and the importance of mental health and emotional power.

Renowned Harvard professor and author Arthur Brooks discusses the keys to happiness, the impact of social media on envy, finding love in the digital age, the importance of complementarity in relationships, the limitations of dating apps, social proof in relationships, breaking the cycle of bad decisions, metacognition and religious contemplation, optimizing dopamine for focus and creativity, unrealistic views of relationships on social media, gratitude for technology and educational podcasts, and the continuous journey of happiness.

Dr. Nathan Bryan, molecular medicine leader, discusses the importance of nitric oxide, therapy for mental health, negative effects of mouthwash on oral microbiome, significance of electrolytes, iodine deficiency, impact of alcohol on oral microbiome, and role of nitric oxide in immune function.

Lily Nichols, a registered dietitian and nutritionist, discusses evidence-based prenatal nutrition. Topics include: best foods during pregnancy, protein intake, plant defense chemicals in our diet, healthy cravings, value of collagen, challenges of eating during pregnancy, benefits of organ meats, food safety concerns, and nutrition during pregnancy and breastfeeding.

Jolene Brighten, a naturopathic endocrinologist, talks about optimizing fertility for both men and women, debunking misconceptions and emphasizing the importance of sperm quality. The podcast also discusses the impact of heat exposure on fertility, benefits of myo-inositol and melatonin supplements, preserving fertility through IVF, risks of twin pregnancies, and the effects of chronic stress on fat cells. They also touch upon hormone replacement therapy for perimenopausal women.