
Two Onc Docs
This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*
Latest episodes

Sep 18, 2023 • 16min
Metastatic Prostate Cancer 2023 UPDATE
Exploring cutting-edge therapies for metastatic prostate cancer including triplet and doublet therapies, radium-223, Lutetium-LU-177 targeted therapy, and genetic testing significance with Drimline testing standards. Also, discussing the importance of supportive care, dental clearance, and monitoring PSA levels for personalized treatment protocols in 2023.

Sep 11, 2023 • 16min
Localized Prostate Cancer 2023 UPDATE
Exploring updates on localized prostate cancer in 2023, including advancements in detection with PSMA PET scans and treatment options based on risk levels. Covering the importance of PSA testing, staging, grading, and understanding treatment approaches for positive lymph nodes.

Aug 28, 2023 • 19min
Metastatic Colon Cancer 2023 UPDATE
This 2023 update on metastatic colon cancer discusses molecular studies, treatment options, and toxicities of Full Fox and Full Theory regimens. It also explores genetic biomarkers, targeted therapies, and treatment approaches for oligometastatic colon cancer.

Aug 21, 2023 • 18min
Localized Colon Cancer 2023 UPDATE
Update on early stage colon cancer, risk factors, hereditary syndromes, staging importance, adjuvant chemotherapy options post-surgery, circulating tumor DNA role in treatment decisions, and detailed follow-up protocols.

Aug 14, 2023 • 19min
Acquired Hemolytic Anemias
This podcast discusses acquired forms of hemolytic anemia, such as warm autoimmune hemolytic anemia, cold agglutinin disease, and paroxysmal cold hemoglobinuria. They explore various types of hemolytic anemia, treatment options, key toxicities of monoclonal antibodies, and important takeaways for distinguishing and treating different types of hemolytic anemia.

Aug 7, 2023 • 14min
Inherited Platelet Disorders
This week’s episode will be focusing on inherited platelet disorders. We will go over the important details on the roles of platelets, the diagnosis of inherited platelet disorders through aggregation studies, as well as the treatment of these disorders.

Jul 31, 2023 • 11min
Primary Myelofibrosis
Discussion on primary myelofibrosis (PMF) and other myeloproliferative neoplasms, including diagnosis, risk stratification, treatment options. Topics include extra-medular hematopoiesis, diagnostic criteria, staging, risk factors, molecular risk, prognosis, supportive care, medication options, stem cell transplant.

15 snips
Jul 24, 2023 • 18min
Esophageal Cancer
Exploring risk factors, diagnosis, and treatment strategies for esophageal cancer. Detailed overview of localized cancer treatment and radiation effects. Discussing different dissection types and various treatment options for metastatic cases.

Jul 17, 2023 • 12min
Polycythemia Vera
This week’s episode will be focusing on another one of the myeloproliferative neoplasms (MPN): Polycythemia Vera (PV). We will go over the important details on the diagnosis, risk stratification, and treatment.

Jul 10, 2023 • 11min
Bone Sarcomas
This podcast dives into the world of Bone Sarcomas, covering topics such as diagnosis, staging, and treatment strategies for osteosarcomas, Ewing sarcomas, and chondrosarcomas. It discusses the rarity of bone sarcomas, the importance of expert biopsies, intensive chemotherapy regimens, limb-sparing surgery considerations, and the challenges of treating resistant chondrocercomas.