

Two Onc Docs
Sam and Karine
This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*
Episodes
Mentioned books

Nov 6, 2023 • 16min
Thrombophilias
This podcast discusses testable thrombophilia syndromes including Antiphospholipid Syndrome, Antithrombin III deficiency, Protein C and S deficiency, Factor V Leiden, and Prothrombin mutations. They cover the presentation, diagnostic testing, and treatment, as well as the impact of medications on protein levels. Additionally, they explore the use of unfractionated heparin during C-sections, combination therapy for women with anti-phospholipid syndrome, and the timing of anticoagulation after delivery.

Oct 30, 2023 • 11min
Metastatic Breast Cancer 2023 UPDATE
The podcast provides an update on metastatic breast cancer focusing on systemic therapy and toxicities. It discusses side effects of CDK46 inhibitors, dosing schedules, and second-line treatment options. Various chemotherapy options for metastatic breast cancer and approaches for HER2 positive and triple negative breast cancer are explored. The role of bone protective agents and the importance of clinical trials are also discussed.

Oct 23, 2023 • 14min
Localized Breast Cancer 2023 UPDATE
Updates on radiation and therapies for localized breast cancer including adjuvant endocrine therapy. Systemic treatment options and importance of timely treatment. Treatment options based on hormone receptor, genomic status and significance of triple negative breast cancer. Genomic status, chemotherapy need, and side effects of medications. Treatment options for HER2 positive breast cancer including neo-adjuvant therapy.

Oct 16, 2023 • 14min
Breast Cancer Screening, Prevention & Intro 2023 UPDATE
This podcast provides high yield tips on breast cancer screening, prevention, and introduces non-invasive breast pathologies. It also discusses treatment options, including surgical procedures and lymph node staging. Key takeaways include screening recommendations, prevention strategies, and risk factors for breast cancer.

Oct 2, 2023 • 10min
Heparin Induced Thrombocytopenia
This podcast explores heparin induced thrombocytopenia, including its pathophysiology, diagnosis, and treatment. Topics include ruling out pseudo thrombocytopenia, understanding the role of heparin and Platelet Factor Four, diagnosing HIT using clinical criteria and additional testing methods, and the use of direct thrombin inhibitors for anticoagulation.

Sep 25, 2023 • 18min
Stem Cell Transplantation
The podcast covers the different types of stem cell transplant, conditioning regimens, and complications. It discusses the use of stem cell transplantation in cancer treatment and finding donors for allogenic stem cell transplant. The importance of umbilical transplant and conditioning regimens is also highlighted. It further explores graft-versus-host disease and various complications that can occur in stem cell transplant patients.

Sep 18, 2023 • 16min
Metastatic Prostate Cancer 2023 UPDATE
Exploring cutting-edge therapies for metastatic prostate cancer including triplet and doublet therapies, radium-223, Lutetium-LU-177 targeted therapy, and genetic testing significance with Drimline testing standards. Also, discussing the importance of supportive care, dental clearance, and monitoring PSA levels for personalized treatment protocols in 2023.

Sep 11, 2023 • 16min
Localized Prostate Cancer 2023 UPDATE
Exploring updates on localized prostate cancer in 2023, including advancements in detection with PSMA PET scans and treatment options based on risk levels. Covering the importance of PSA testing, staging, grading, and understanding treatment approaches for positive lymph nodes.

Aug 28, 2023 • 19min
Metastatic Colon Cancer 2023 UPDATE
This 2023 update on metastatic colon cancer discusses molecular studies, treatment options, and toxicities of Full Fox and Full Theory regimens. It also explores genetic biomarkers, targeted therapies, and treatment approaches for oligometastatic colon cancer.

Aug 21, 2023 • 18min
Localized Colon Cancer 2023 UPDATE
Update on early stage colon cancer, risk factors, hereditary syndromes, staging importance, adjuvant chemotherapy options post-surgery, circulating tumor DNA role in treatment decisions, and detailed follow-up protocols.