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Two Onc Docs

Non-Melanoma Cutaneous Malignancies

Mar 4, 2024
Explore the world of non-melanoma cutaneous malignancies such as squamous cell skin cancer and basal cell carcinoma. Get insight into staging, diagnosis, and treatment options, including the importance of thorough workups for suspicious lesions. Learn about high-risk skin cancers, treatment options for unresectable or metastatic cases, and the importance of complete tumor removal for basal cell carcinomas.
11:41

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Quick takeaways

  • Treatment for high-risk cutaneous squamous cell carcinoma includes surgery and adjuvant radiation based on extent of perineural involvement.
  • Hedgehog inhibitors like vismodegib are crucial in managing unresectable or metastatic basal cell carcinoma.

Deep dives

Key Points on Cutaneous Malignancies

Basal cell carcinoma and cutaneous squamous cell cancer are the most common types of non-melanoma skin cancers. Risk factors for cutaneous squamous cell cancer include UV exposure, older age, and immunosuppressive treatments. Local regional therapies are often curative for these cancers, with medical oncology involvement required in some cases.

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