Louise Perry, journalist and author, discusses the dangers of casual sex for women, importance of trusting instincts, impact of dating apps on men, truth about sex on first dates, physical differences between genders, repercussions of casual sex on society, lack of communication hurting both genders, women's icks towards men, importance of women listening to instincts, societal views on gender roles in certain jobs

Renowned leadership expert Simon Sinek and host Steven Bartlett dive into the impact of loneliness on addiction, the struggle to make friends, the importance of national service, the rise of individualism, and the significance of acts of service. They discuss the difference between friendships and relationships, the importance of belief, and the direction young people should aspire towards. The conversation also touches on the challenge of balancing relationships with achievements, the necessity of human connection in the workplace, and the power of storytelling for effective communication.

Dr. Mindy Pelz, a nutritionist and functional health expert, discusses the menstrual cycle, highlighting key phases and hormone fluctuations. She emphasizes the importance of understanding these cycles for men to support women better. Dr. Pelz provides tips on how men can be more caring and attentive throughout the cycle, promoting empathy and improved relationships.

Dr. Lisa Mosconi discusses the impact of menopause on the brain, the correlation between menopause and Alzheimer’s, importance of sex hormones for brain health, and the truth about hormone therapy. Topics include brain scans, behavioral changes, brain fog, menopause stages, and the link between suicides and menopause in women.

Simon Cowell, renowned music mogul, shares his journey from bankruptcy to success, emphasizing hard work, respect, and trusting gut instincts. He discusses the importance of loyalty, fatherhood, and balancing work-life, along with overcoming setbacks like financial struggles and a life-threatening accident. Cowell reflects on the impact of loss, regrets in the music industry, and the future of entertainment amidst AI advancements.

Leading professor of evolutionary biology, David Raichlen, discusses how different types of exercise can provide various neurological benefits. Research shows that a combination of physical and cognitive challenges is ideal for brain function, mimicking how humans evolved. Choosing outdoor activities over the treadmill and trying new routes can enhance mood, memory, and concentration.

Former U.S. Secret Service Agent, Evy Poumpouras, shares insights on detecting lies, gaining control over others, and building confidence. She discusses her experiences working for 4 U.S. Presidents, ways to tell if someone is lying, and the importance of boundaries and respect in leadership roles.

Dr. Natalie Crawford, a fertility doctor, discusses the impact of plastic on fertility, men's declining sperm count, environmental factors affecting fertility, the effects of phones and hot baths on sperm count, the importance of sleep for reproductive hormones, and the best diets for good fertility.

Dr Aditi Nerurkar discusses 'Popcorn Brain' caused by excessive phone use, the importance of setting digital boundaries, and strategies to improve mental health by reducing phone dependency. She also touches on the psychological impact of consuming graphic content on social media and maintaining mental health amidst distressing news.

Dr Mike, known as the ‘Sexiest Doctor Alive’, discusses debunking online health trends, dangers of vaping, fitness benefits, mental health struggles, coping with grief, pitfalls of supplement dependency, and navigating the complex world of healthcare and medical trust.