James Sexton, a world-renowned divorce lawyer and author, dives deep into the common pitfalls leading to marital breakdowns. He explores how 'slippage'—the tendency to prioritize children over each other—can jeopardize relationships. Sexton shares insights on the significant links between sexual satisfaction and divorce, the emotional challenges surrounding breakups, and the transformative journey of acceptance during such times. He emphasizes that open communication, especially regarding prenuptial agreements, can be crucial for maintaining a healthy marriage.

Russ Cook, an ultramarathon runner and author, made history by running 10,000 miles across Africa in just 352 days. In the heart of the Democratic Republic of Congo, he faced armed threats and even a kidnapping, sharing the emotional turmoil of that harrowing experience. Beyond survival, he reflects on confronting personal fears and realizing profound truths about himself. Russ's journey isn't just about physical endurance; it's a powerful testament to facing life's challenges head-on.

Dr. Ann McKee, a leading neurologist and director at Boston University’s CTE and Alzheimer’s Disease Research Centres, brings her extensive research on Chronic Traumatic Encephalopathy (CTE) to the forefront. She exposes the hidden dangers young athletes face in contact sports, detailing how repeated head injuries lead to devastating health risks. McKee shares compelling stories of athletes affected by CTE and discusses the NFL's reluctance to acknowledge the severity of the problem, urging for greater awareness and preventive measures to protect future generations.

Dr. Rena D. Malik, a urologist and sexual health expert, Dr. Alok Kanojia, a Harvard-trained psychiatrist focused on digital addictions, and Erika Lust, an independent adult filmmaker, engage in a spirited debate about the pervasive influence of pornography. They discuss how porn may impact relationships, the psychological effects of addiction, and the ways it rewires the brain. The conversation dives into the nuances of sexual satisfaction, the concept of 'death grip syndrome,' and the quest for more authentic representations in adult content.

Dr. Mindy Pelz, a fasting and hormone expert, sheds light on liver health and nutrient needs. She shares intriguing signs of liver function tied to everyday observations, like yellowing eyes and dry feet. Mindy explains how these symptoms can indicate poor detoxification due to nutrient deficiencies. She emphasizes the impact of minerals and suggests combining fasting with a diet rich in fruits and vegetables to restore balance. Dive into her practical tips for daily self-assessments for better health!

Trevor Noah, comedian and former host of The Daily Show, shares his gripping journey from surviving Apartheid to navigating fame. He reveals how childhood trauma and being born into a racially divided society shaped his identity. Trevor opens up about his mother's resilience after a violent incident and discusses the intense pressures he faced, including death threats. The conversation tackles men's mental health, the loneliness epidemic, and the significance of genuine connection in overcoming life's challenges.

Join Ramit Sethi, a personal finance expert and host of Netflix's 'How to Get Rich,' as he dives into the intersection of money and relationships. He argues why renting can be smarter than buying a home and reveals key financial red flags in partnerships, like being cheap. Ramit emphasizes the importance of financial conversations in relationships, offering insights on different money types and the unique challenges couples face when discussing finances. Tune in for strategies to reshape your view on wealth and foster healthier financial dynamics!

Guy Raz, host of "How I Built This," shares his insights on entrepreneurship and the daunting challenges business owners face. He emphasizes resilience and self-belief as crucial for overcoming rejection, using inspiring stories from successful figures. The conversation explores luck's pivotal role in success and the strategic power of quitting at the right moment. Additionally, Raz discusses the importance of partnerships in both life and business, illustrating how emotional support can fuel entrepreneurial journeys. His reflections highlight that failure often paves the way for unexpected opportunities.

Boris Johnson, former Prime Minister of the UK, dives deep into his tumultuous political life. He shares his candid thoughts on supporting Brexit without a plan and reflects on the chaotic pandemic response, including ‘Partygate’. Johnson reveals insights on zoonotic diseases and the origins of COVID-19, hinting at the serious discussions amongst leaders. He also touches on the socio-economic disparities in the UK and his perspective on the future of politics amid high-profile international figures.

Thomas Seyfried, a biology and genetics professor at Boston College, dives into groundbreaking cancer research. He argues that cancer should be viewed as a metabolic disease influenced by diet rather than just genetics. Seyfried reveals the alarming global rise in cancer cases and explores the significant role of blood sugar and modern eating habits in cancer growth. He emphasizes the benefits of calorie restriction, exercise, and ancestral dietary practices in prevention and management. This conversation challenges conventional views and advocates for a shift toward metabolic therapy.