Run the List

In this episode of Run the List, Joyce Zhou (host) and Blake Smith (case presenter) talk with Dr. Jean Connors, a hematologist at Brigham and Women’s Hospital and Dana Farber Cancer Institute, about the causes of thrombophilia (congenital and acquired) and its management in the acute care setting. We learn about common risk factors and how these can be both additive and synergistic with inherited causes of thrombophilia. The episode closes with Dr. Connors’ discussion of both when to order lab tests and how to interpret them in the setting of VTE, in addition to important clinical pearls to consider with any case of known or suspected thrombophilia. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

In this episode of Run the List, Joyce Zhou (host) and Katie Kester (case presenter) discuss sickle cell disease and the management of acute chest syndrome with Dr. Maureen Achebe, a hematologist at Brigham and Women’s Hospital and Dana Farber Cancer Institute. We learn not only about the management and common complications of sickle cell but also some of the challenges that patients with sickle cell face in accessing care and how best to advocate for these patients. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Marlise Luskin, a hematologist/oncologist at the Dana-Farber Cancer Institute, joins host Walker Redd and case presenter Jakub Glowala to discuss a case of a febrile neutropenia (FN) in a patient with AML. Dr. Luskin first defines neutropenia, then fever, and moves to the chronicity of FN. Using these definitions, Dr. Luskin talks about ways to identify which pathogens are more likely associated with acute vs. chronic FN presentations. They then walk through the standard workup of a patient with FN, talk about which tests/procedures to avoid, and which to later include when fevers do not resolve after empiric treatment. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Aric Parnes, a hematologist at Brigham and Women’s Hospital and the Dana-Farber Cancer Institute, joins host Joyce Zhou and case presenter Sarah Onorato to talk through a case of a patient presenting with new onset pancytopenia. Throughout the case, they discuss a framework for thinking through the major causes of pancytopenia. In addition, they consider the steps in emergent management of severe pancytopenia and an approach to history taking, physical examination, and data interpretation for patients with pancytopenia. Tune in to hear their discussion, including the patient’s final diagnosis and Dr. Parnes’ three clinical pearls for pancytopenia! Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Robert Stern, a hematologist at Brigham and Women's Hospital, discusses thrombocytopenia with Dr. Navin Kumar (host) and Sarah Onorato (script writer and case presenter). He discusses a clinical framework to diagnosis, initial considerations on management, and key considerations and management points for the patient case. They wrap up with high yield clinical pearls. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Arielle Langer, a hematologist at Brigham and Women's Hospital, discusses her approach to diagnosing anemia and applies it to clinical cases with Joyce Zhou (host) and Jordan Said (scriptwriter and case presenter). They step through the important history-taking and lab findings necessary to evaluate a patient with anemia and discuss how to bring these elements together to inform a wide differential diagnosis. The group also offers some high-yield points to consider for the treatment of specific causes of anemia. The episode concludes with clinical pearls from Dr. Langer and final tips from Jordan. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. OP Hamnvik, an endocrinologist and the Director of the Center for Oncoendocrinology at Brigham and Women's Hospital (BWH), discusses his career to becoming an endocrinologist with Blake Smith (host). Originally from Norway, Dr. Hamnvik takes us around the globe as he began his journey as a medical student in Ireland, followed by residency and fellowship at BWH in Boston. He now runs the endocrinology fellowship at BWH, in addition to educating thousands of students and faculty through his role as the Education Editor at the New England Journal of Medicine (NEJM). Outside of education, he has a particular interest in caring for transgender patients, in addition to seeing cancer patients at the Dana-Farber Cancer Institute whose immune therapy (checkpoint blockade) has resulted in autoimmune endocrinopathies. Dr. Hamnvik closes the episode with a few takeaways for listeners interested in pursuing a career in endocrinology, in addition to some tips for our international student following who might want to pursue future clinical training in the US! Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. OP Hamnvik, an endocrinologist and the Director of the Center for Oncoendocrinology at Brigham and Women's Hospital, discusses transgender health from the endocrinologist’s perspective with Joyce Zhou (host) and Jordan Said (script writer and case presenter). They discuss the central tenets of caring for a transgender patient, the agents used for gender-affirming hormone therapy, and the long-term monitoring and management of these patients. The episode ends with some clinical pearls from both Jordan and Dr. Hamnvik. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Anand Vaidya, an endocrinologist and the director of the Center for Adrenal Disorders at Brigham and Women's Hospital, discusses adrenal insufficiency with Dr. Navin Kumar (host) and Bina Kassamali (script writer and case presenter). They discuss the presentation of adrenal insufficiency (AI) and its triggers, a framework for primary vs. secondary causes of AI, an endocrine work-up for AI and related diseases, and the management of AI with steroids and patient education. Dr. Vaidya also makes a brief note on adrenal crises. The episode ends with some clinical pearls from both Bina and Dr. Vaidya. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Nadine Palermo, an endocrinologist and the Associate Director of the Acute Diabetes Care program at Brigham and Women’s Hospital, talks with Joyce Zhou (host) and Jakub Glowala (case presenter) to discuss acute hyperglycemic episodes. The discussion begins with a case of a patient presenting with dehydration, altered mental status, emesis, and suspected symptomatic hyperglycemia. Dr. Palermo then brings us up to speed on the pathophysiology behind diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS), underscoring the role of osmotic diuresis and counter-regulatory hormones in exacerbating the two conditions. Dr. Palermo instructs us on the “classic” signs of a patient presenting with DKA, while cautioning us against relying solely on these textbook findings, as the workup often involves a holistic combination of BMP, urinalysis, ABG/VBGs, and history-taking. The episode closes with a discussion of DKA and HHS treatment, in addition to some clinical pearls. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands