Run the List

Dr. OP Hamnvik, an endocrinologist and the Director of the Center for Oncoendocrinology at Brigham and Women's Hospital, discusses transgender health from the endocrinologist’s perspective with Joyce Zhou (host) and Jordan Said (script writer and case presenter). They discuss the central tenets of caring for a transgender patient, the agents used for gender-affirming hormone therapy, and the long-term monitoring and management of these patients. The episode ends with some clinical pearls from both Jordan and Dr. Hamnvik. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Anand Vaidya, an endocrinologist and the director of the Center for Adrenal Disorders at Brigham and Women's Hospital, discusses adrenal insufficiency with Dr. Navin Kumar (host) and Bina Kassamali (script writer and case presenter). They discuss the presentation of adrenal insufficiency (AI) and its triggers, a framework for primary vs. secondary causes of AI, an endocrine work-up for AI and related diseases, and the management of AI with steroids and patient education. Dr. Vaidya also makes a brief note on adrenal crises. The episode ends with some clinical pearls from both Bina and Dr. Vaidya. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Nadine Palermo, an endocrinologist and Associate Director of Acute Diabetes Care at Brigham and Women's Hospital, dives deep into acute hyperglycemic episodes. She elucidates the pathophysiology and risks of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS), stressing the importance of a comprehensive diagnosis which goes beyond textbook signs. Treatment strategies including fluid management and insulin timing are discussed, alongside clinical pearls that reveal DKA's presence in varied diabetes cases.

Dr. Nadine Palermo, an endocrinologist and Associate Director of the Acute Diabetes Care program at Brigham and Women’s Hospital, shares her expertise on managing diabetes in hospitalized patients. She discusses the importance of identifying hyperglycemia types and customizing treatment plans based on individual patient factors. Dr. Palermo also delves into the use of both insulin and emerging non-insulin agents, emphasizing tailored weight-based dosing strategies. Discover how effective management can significantly influence patient outcomes during hospital stays.

Dr. Anna Goldman, an endocrinologist and medical educator at Brigham and Women’s Hospital, talks with Joyce Zhou (host) and Dr. Emily Gutowski (case presenter) to discuss diagnosis, management, and lifestyle considerations in patients with diabetes mellitus. They talk through a case of a patient with hypertension, hyperlipidemia, and a family history of T2DM. Dr. Goldman presents her framework for type 1 vs. type 2 DM and how to diagnose T2DM based on labs, physical exam findings, and clinical history. Moreover, Dr. Goldman teaches us about the various pharmacologic agents used in T2DM treatment (metformin, sulfonylureas, DPP4i, GLP1R agonists, SGLT2i) from their mechanisms of action and side effects to their different clinical uses. Dr. Goldman closes the conversation by discussing what her follow-up visit looks like both in history-taking and physical examination, in addition to any treatments that need to be considered. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. OP Hamnvik, an endocrinologist and medical educator, joins the hosts to discuss hypocalcemia. They cover its causes, clinical manifestations, and physical exam signs, along with the metabolism of vitamin D and its deficiency. The importance of vitamin D supplementation and treatment for hypokalemia is also discussed.

Run the List dedicates this episode to George Floyd, Ahmaud Arbery, Breonna Taylor, and others that have been tragically lost due to structural racism within our society.In this important episode, Dr. Navin Kumar talks with Dr. Utibe Essien, an Assistant Professor of Medicine at the University of Pittsburgh School of Medicine and a researcher who dedicates much of his time to racial and ethnic health disparities. In it, Dr. Essien educates us on the discipline of health disparities, talking about its early history from 1899 through today, and advocates for its place in medical school curricula, as social determinants of health are a critical piece of disease pathophysiology. The two touch on the social structures that drive disease admissions and presentations, using COVID-19 as a prominent example of the social inequities that exist within our society. Moreover, they discuss structural racism and how we as a medical community can step up to respond and make an impact. We can’t go on as "business-as-usual” and Dr. Essien provides us with practical short-term and long-term steps to take in order to take better care of our patients and one another. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. OP Hamnvik, an endocrinologist and medical educator at Brigham and Women’s Hospital, joins Emily Gutowski (host) and Joyce Zhou (case presenter) to discuss hypercalcemia. Through a case of an outpatient presenting with incidental hypercalcemia and no symptoms, Dr. Hamnvik walks through ways to differentiate the various causes of hypercalcemia, from primary hyperparathyroidism to non-PTH-mediated sources such as malignancy. Together, they discuss the normal regulation of calcium in the body and explore the ways in which various labs can be used in conjunction to pinpoint the diagnosis, paying attention to possible laboratory artifacts. The conversation closes with ways to manage both inpatient and outpatient hypercalcemia, in addition to learning several clinical pearls from Dr. Hamnvik! Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Rachel Blair, an endocrinology fellow at Brigham and Women’s Hospital, joins Emily Gutowski (host) and Katie Kester (case presenter) to discuss hyperthyroidism. Together, they walk through a case of a young patient with suspected thyrotoxicosis and discuss the diagnostic workup, from physical exam and labs to radioactive iodine uptake studies. They talk through causes of primary and secondary hyperthyroidism, when thyrotoxicosis is considered an endocrine emergency, and how to provide initial empiric management of patients with suspected hyperthyroidism while awaiting thyroid antibody tests. The conversation closes with Dr. Blair’s three major clinical takeaways, but you’ll have to tune in to find out! Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands

Dr. Rachel Blair, an endocrinology fellow at Brigham and Women’s Hospital, joins Dr. Navin Kumar (host) and Sarah Onorato (case presenter) to discuss hypothyroidism. Together, they use a sample case of a patient with hypothyroidism as a framework to guide discussion about primary vs. secondary hypothyroidism, associated lab findings, and management of unambiguous hypothyroidism vs. subclinical hypothyroidism. They wrap up their discussion with several clinical pearls, advocating for both a broad differential and panel of lab studies, assessed over time, to cinch the diagnosis. Our Sponsors:* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.comAdvertising Inquiries: https://redcircle.com/brands