Dr. OP Hamnvik, an endocrinologist and the Director of the Center for Oncoendocrinology at Brigham and Women's Hospital, discusses transgender health from the endocrinologist’s perspective with Joyce Zhou (host) and Jordan Said (script writer and case presenter). They discuss the central tenets of caring for a transgender patient, the agents used for gender-affirming hormone therapy, and the long-term monitoring and management of these patients. The episode ends with some clinical pearls from both Jordan and Dr. Hamnvik.