

High Performance Longevity
Nick Urban | Longevity, Biohacking, & Performance
High Performance Longevity is the show for folks dedicated to maximizing their overall quality of life. I am your host Nick Urban and I’m bringing you the best minds handpicked from cognitive enhancement, BioHarmonization (biohacking 3.0), fitness, ancestral health, herbal medicine, spirituality, personal development, longevity, supplementation, and meditation.
Each episode deconstructs their world-class work into tangible steps for you to look, feel, and perform your best. We’ll leave no stone unturned whether modern topics like peptides and nootropics, or ancient systems like Ayurveda and Traditional Chinese Medicine. You’ll learn how to re-sculpt your body, boost energy levels, improve athletic performance, and gain mental clarity.
Nick Urban is a certified Chek Practitioner, biohacker, performance coach, and has spent a decade studying high performance. Health nut or not, HPL will fill your toolbox with products, tactics, knowledge, and resources needed to live at your maximum potential.
Previously, this show was called Mind Body Peak Performance.
Each episode deconstructs their world-class work into tangible steps for you to look, feel, and perform your best. We’ll leave no stone unturned whether modern topics like peptides and nootropics, or ancient systems like Ayurveda and Traditional Chinese Medicine. You’ll learn how to re-sculpt your body, boost energy levels, improve athletic performance, and gain mental clarity.
Nick Urban is a certified Chek Practitioner, biohacker, performance coach, and has spent a decade studying high performance. Health nut or not, HPL will fill your toolbox with products, tactics, knowledge, and resources needed to live at your maximum potential.
Previously, this show was called Mind Body Peak Performance.
Episodes
Mentioned books

Oct 24, 2024 • 1h 6min
#180 Ultimate 60-Second Strategy to Cut Stress, Anxiety, Enhance Recovery & Improve Performance (Vagus Nerve Electric Stimulation) | Nick Hool @ Hoolest
Are you a stress dominant individual looking for a quick way to reduce anxiety & nerves right before your big game, board meeting or a high stake activity? Then vagus nerve stimulation may be the answer.
In today’s episode, Nick Hool, founder and innovator of Hoolest, unfolds the truth about the vagus nerve stimulation & just how crucial your vagal nerve tone & condition is when it comes to your reactions to stress. Discover how he developed a device targeting the vagus nerve that promotes relaxation & reduces stress in under 60 seconds. You’ll learn all that & more in this episode on “Innovating Vagus Nerve Stimulation”
Meet our guest
Nick, a former competitive golfer, shifted his focus to studying stress responses in high-performance individuals after developing debilitating performance anxiety. He earned a Ph.D. in biomedical engineering at ASU, where he explored neuromodulation technologies and discovered the benefits of vagus nerve stimulation for calming the nervous system.
To improve user experience, he developed VeRelief, a portable, high-strength vagus nerve stimulation tool designed for busy professionals seeking effective stress relief. VeRelief is now used by first responders, executives, athletes, doctors, and other high-stress professionals nationwide.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
There are many ways to stimulate the vagus nerve, each with slightly different effects
The vagus nerve connects the brain to the body and helps calm the nervous system during fight-or-flight states
Electrical stimulation is faster and more effective for vagus nerve activation
Stimulating the trigeminal nerve can reduce headache pain and prevent future migraines
Auricular nerve stimulators can be used for 10–20 minutes; simply adjust them until you hit the right spot for effectiveness
Vagus nerve stimulation can reduce stress and anxiety
Vagus nerve stimulation can distract your mind from stress by focusing your attention on the sensation
Sleep issues often have a stress component, such as overthinking, mental chatter, or negative thoughts
Auriculovagus nerve stimulation increases neuroplasticity, enhancing the brain’s ability to learn and retain new information
Using vagus nerve stimulation before practicing a skill improves memory retention and performance
If you have low vagal tone, start gently with electrical stimulation, as it can be overwhelming at first
Visualization can help reduce stress by mentally rehearsing scenarios, making the brain feel like it’s already experienced them
Effective visualization requires time and focus—an hour a day of undistracted practice is necessary to see real benefits
Daily vagus nerve stimulation strengthens emotional regulation, reducing negative responses to future bad memories
Episode Highlights
03:06 Everything You Need to Know About The Vagus Nerve
07:01 Benefits & Risks of Vagus Nerve Stimulation
09:04 Vagus Nerve & Stress Relief Stimulation Modalities
18:49 Effects of VNS on Chronic Illness, Cognitive, & Performance Enhancement
47:41 Vagus Nerve Stimulation Studies
Links
Watch it on YouTube: https://youtu.be/kw1vqd_ABC4
Full episode show notes: mindbodypeak.com/180
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Nick

Oct 17, 2024 • 1h 1min
#179 Urine Therapy: Your Perfect Medicine For Natural Stem Cells, Hormone Balance & Detox? | Darlene Teahen @ The Vitality Expert
Did you know that some people believe drinking your own pee can boost your health?
Urine therapy, an ancient practice, is said to help detoxify the body, strengthen the immune system, and improve skin conditions. Proponents claim that it can provide natural antibodies, hormones, and nutrients that may be lost through urination.
While this practice is controversial and lacks strong scientific backing, it's been used in various cultures for centuries as a form of alternative healing. Learn more about this topic in today's episode on 'Urine Therapy'.
Meet our guest
Darlene Teahen earned a Bachelor's Degree in Fine Arts with a minor in Business from Mount Allison University in 1997. After a life-changing event in 1998, she became a volunteer firefighter & First Responder, which sparked her interest in holistic health.
Motivated by her daughter’s health challenges & preventable illnesses in her community, she researched alternative treatments & nutrition, leading to her family’s improved health. Darlene then pursued a career as a Naturopathic Practitioner, earning a Doctorate in Holistic Health, & is now working on her PhD in Natural Medicine.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Urine is full of stem cells & is pushed out of allopathic medicine since it can’t be patented
All body fluids are "dirty," but urine comes from a different system, containing hormones, vitamins, & minerals, making it homeopathic
Even with a UTI, urine can benefit you due to its homeopathic properties—plasma ultrafiltrate is more sterile than blood
Healthier plasma leads to healthier cells & body; urine is essentially plasma
Many consumer products, including creams & medications, are derived from urine
Urine therapy has shown consistent improvements, including reduced inflammation, better sleep, lower stress, improved heart rate, & oxygen levels
Heavy metals are primarily eliminated through feces, aided by chelators like chlorophyll or zeolite
Urine contains hormones, neurotransmitters, peptides, & bioactive compounds in the exact amounts your body needs
Both men & women face hormonal imbalances, but often men don’t notice it, mistaking issues like hair loss & ED as aging, which is often due to imbalance
Hormonal imbalances aren’t normal; menopause doesn’t have to involve suffering if everything is balanced
Aged urine is stronger & richer in stem cells, but may cause a deeper reaction
Episode Highlights
5:45 The Controversial Way to Heal Your Body
12:10 The Research Behind Urine Therapy
20:13 Health Benefits of Urine Therapy
26:33 Debunking Myths About Urine Therapy
40:16 Practical Ways to Get Started with Urine Therapy
Links
Watch it on YouTube: https://youtu.be/78fW-NzaSm0
Full episode show notes: mindbodypeak.com/179
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Nick

Oct 10, 2024 • 1h 14min
#178 Fight Pain, Boost Dopamine, Relieve PTSD & How Ironmen Athletes Recover From Training, Biohacks to Amplify Cold Therapy | Joshua Church @ Edge Theory Labs
Are you aware that you can fight your pain by mastering the cold? Boost endurance and shorten recovery time by plunging in ice water?
In this episode, Joshua Church from Edge Theory Labs talks about the incredible effects of cold therapy. Revealing how the Wim Hof Method helps the body find balance & shares the science behind contrast therapy.
Learn how cold immersion plays a key role in pain recovery & listen to expert advice from our guest in today’s episode on “The Ultimate Guide to Cold Therapy” as we explore the secrets of cold exposure for better recovery, sharper focus, and a healthier, more resilient lifestyle.
Meet our guest
Joshua Church is the co-founder of Edge Theory Labs, where he developed the world’s first portable “iceless ice bath” with advanced features like filtration and a hot-tub mode. He leads workshops, retreats, and experiences to help people thrive by sharing tools for health, happiness, and success.
He hosts the Find The Others podcast and emphasizes growth through community. In 2024, he was recognized on the Forbes 30 Under 30 list and completed his first Ironman Triathlon in 2023.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Cold therapy reduces inflammation, speeds recovery, boosts energy, and improves focus
Cold therapy increases dopamine by 250% & norepinephrine by 530%
Three minutes, four times a week (12 minutes total) is a solid baseline for cold exposure
Cold is just a sensation—bring full awareness to it rather than avoiding it
Research often overlooks the introspective side of cold exposure
Going inward during cold therapy yields most of the benefits
Liberation comes from allowing yourself to step outside the norm
Cold immersion research lacks female representation
The myth is that cold therapy must be extreme or for pro athletes to work
Episode Highlights
10:17 The Fundamentals of Cold Therapy
25:10 Benefits of Cold Therapy
34:34 Cold Therapy Tips & Practices
37:29 Dosing Cold Immersion
Links
Watch it on YouTube: https://youtu.be/X8vCJz2sF0I
Full episode show notes: mindbodypeak.com/178
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Nick

Oct 3, 2024 • 1h 12min
#177 Insights From the World’s Largest Longevity Database & Personalized Tools to Slow Your Aging (Cellular Health, Lifestyle & Supplements) | Chris Mirabile @ Novos Labs
Ever wondered why some people seem to age faster while others barely slow down?
Unpack the 12 hallmarks of aging, highlighting how hidden factors like inflammation & genomic instability could be sabotaging your health. But here’s the good news: by adopting core lifestyle habits & understanding how supplementation really works, you’ll take control of your aging process.
With Chris Mirabile of Novos Labs, you’ll gain insights from the largest database of longevity enhancing practices & how to fine-tune your routine for a longer, healthier life. Dive into all that & more in today’s episode on ‘Novos Labs Longevity’
Meet our guest
Chris Mirabile is a serial entrepreneur, brain tumor survivor, & the youngest winner of NYU Stern’s business plan competition. He co-founded multiple successful startups, including a real estate tech platform serving clients with over half a trillion USD in assets & Hotlist, a social platform that attracted interest from Google & Facebook.
Driven by his passion for health & wellness, Chris turned his focus to longevity after surviving a brain tumor. As a “citizen scientist,” he spent over a decade researching aging & experimenting with lifestyle hacks. This journey led him to found NOVOS, the first nutraceutical company targeting the 12 biological causes of aging. NOVOS features a scientific advisory board with top biologists & geneticists from Harvard, MIT, & The Salk Institute, creating a biotech platform that empowers people to enhance their healthspan & lifespan.
Thank you to our partners
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Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Most supplement companies are primarily marketing-focused, not scientific or biotech-driven
Combining ingredients can produce unexpected effects on the body
Scientific studies should validate whether ingredient combinations are synergistic, rather than relying on marketing assumptions
Negative synergy (dyssynergy) occurs when a combination of ingredients makes the result worse
Feeling younger or looking better from HGH doesn’t guarantee long-term health; it may actually be harmful
Some antioxidants act as pro-oxidants, leading to an increase in the body's own antioxidants
While you may feel a product works, negative biological effects might occur unnoticed
Phosphatidyl inositol helps with stress & may benefit women with severe menstruation or hormonal issues
About 70% of people are deficient in magnesium
The supplement is designed for both biohackers & the average American, not just for obese individuals
Tterastylabine is better absorbed through the gut & has a longer half-life in the blood than resveratrol, making it more effective
Episode Highlights
06:23 Understanding The Truth About Longevity
17:07 What You Need to Know About Longevity Supplements
35:12 Behind The World's Largest Longevity Database
45:16 Longevity Practices To Start Your Journey
Links
Watch it on YouTube: https://youtu.be/CrcktKY9GlE
Full episode show notes: mindbodypeak.com/177
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Nick

Sep 26, 2024 • 1h 11min
#176 Are Your Supplements Made of Coal Tar? Natural vs Synthetic Mineral Sources, The Great Magnesium Scam & Misleading Marketing | Dr. Carolyn Dean @ RnA ReSet
Your supplements are not doing what it’s supposed to & misleading marketing tactics may be the culprit.
In today’s episode, you’ll explore the secrets of synthetic vitamins in your cupboard & discover which natural forms are better for your body. We’ll break down the effects of supplement marketing, misunderstood ratios of calcium to magnesium as well as how everyday habits like saunas or ice baths might be depleting your nutrients.
Strike the right balance of essential minerals to support your overall health, rethink your supplement routine & align your wellness with what your body really needs. Find out how & more on today’s episode on Whole Foods vs Synthetic Supplements.
Meet our guest
Dr. Carolyn Dean, a medical doctor, naturopath, and renowned author has dedicated over five decades to merging medical science with the healing gifts of nature. Her mission is to empower individuals to enhance their well-being, boost energy levels, and manage their health effectively.
Following her acclaimed work “The Magnesium Miracle®,” initially published in 2004 & revised in 2017, she now presents her latest revision, “Magnesium: The Missing Link to Total Health®.”
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Lacking essential nutrients makes us more vulnerable to pathogens
Intense detox methods like ice baths or saunas can deplete minerals in already deficient people, worsening their condition
Ions always form compounds due to their charge
Current medicine lacks ionized blood testing; standard tests don’t measure magnesium activity in the mitochondria
Magnesium is often overlooked, yet it’s crucial for many bodily functions, like producing nitric oxide
Nine key minerals are required for proper thyroid hormone production
Drinking sea-salted water helps reduce edema by delivering essential minerals for hydration
Fluoride binds to magnesium, forming brittle compounds that accumulate in tendons, ligaments, & joints
Mineral deficiencies leave the body susceptible to heavy metal toxicity
Poorly absorbed calcium supplements can lead to artery calcification & increased heart disease risk
High doses of vitamin D can cause magnesium deficiency, as magnesium is needed to metabolize it
Energy medicine requires sufficient minerals to be effective
Episode Highlights
9:26 The Role of Magnesium & Minerals for Your Overall Health
18:15 Natural vs Synthetic Supplementation
33:36 The Truth About the Supplement Market
41:29 Methods to Remineralize Your Body Effectively
Links
Watch it on YouTube: https://youtu.be/AS2-eNNqt8k
Full episode show notes: mindbodypeak.com/176
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Nick

Sep 19, 2024 • 1h 19min
#175 Use Younger Cells to Heal Your Older Body with Regenerative Medicine (Stem Cells, PRP, Exosomes & Prolotherapy) | Dr. Jeff Gross @ ReCELLebrate
Did you know that you possess the ability to heal your current self the way your younger version did?
Explore ground-breaking regenerative treatments with Dr. Jeff Gross from ReCELLebrate. With exosomes & stem cells, your body can heal faster & better.
Find out how having a diverse microbiome & high-quality supplements like magnesium & omega-3s bioharmonizes your health while also shedding light & understanding the importance of preventative measures against inflammation & the advantage of fine-tuning your body's recovery processes for a better, healthier life.
Learn about this & more in today’s episode on ‘Regenerative Medicine’.
Meet our guest
Dr. Jeff Gross, the "Stem Cell Whisperer," attended George Washington University Medical School, where his research on nested PCR has advanced viral infection diagnostics, including COVID-19. He trained at top trauma centers & completed a spinal biomechanics fellowship under Dr. Ed Benzel. His research on brain tissue's optical properties has been cited nearly 500 times.
Dr. Gross has published extensively in clinical medicine, neuroscience, biomedical optics, AI, & stem cell medicine. He treats neurosurgery patients, focusing on non-surgical & regenerative medicine, while consulting internationally. He’s donated over $100 million in patient care & advocates against health insurance fraud. Recently, he authored the spine chapter of a regenerative stem cell medicine textbook & speaks at major biohacking conferences.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Aging is the accumulation of chronic inflammation in cells & tissues, leading to degeneration
Slowing the inflammatory & degenerative process can reduce the risk of disease. The earlier & more proactive you are, the better
Melatonin, cortisol's opposing hormone, decreases significantly after puberty
Acute inflammation helps build resilience
Chronic inflammation reduces the function & volume of our stem cell reserves
Most body tissues originate from the mesoderm, which forms the middle tissues (mesenchyme)
Before expensive procedures, address factors rapidly depleting your stem cells naturally to enhance treatment effectiveness
Cells lose their ability to function properly, produce the right proteins, & can become "zombie cells" when severely damaged
The body contains many peptides, like insulin, endorphins, melatonin, & others used for weight loss, anti-aging, & anti-inflammatory purposes
Episode Highlights
3:30 Everything You Need to Know About Inflammation
28:14 Regenerative Medicine Therapies & Techniques
37:34 Exosomes vs Stem Cells Explained
52:04 Supplementation, Resources & Other Alternatives
Links
Watch it on YouTube: https://youtu.be/ThzjGurRkvU
Full episode show notes: mindbodypeak.com/175
Connect with Nick on social media
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Nick

Sep 12, 2024 • 1h 6min
#174 Navy SEAL’s Top Tips for Harnessing Stress to Build Courage, Wipe Out Fear & Stop Anxiety Cold | Christopher Maher @ True Body Intelligence
Ever wondered how to turn the stress in your life into a catalyst for personal growth?
Explore the powerful insights of today’s guest, Christopher Maher on bioharmonizing stress for optimal living. By integrating positive stress management tools like yoga, breath work, & structured routines, you transform anxiety into growth. Act on these strategies to achieve a clear mind & renewed energy in your day to day life.
Discover the importance of alone time for emotional clarity & learn to communicate your needs for better support in today’s episode on Stress-free Living
Meet our guest
Christopher Lee Maher, a former Navy SEAL & Olympic hopeful, discovered the detrimental effects of accumulated stress on his health despite being physically fit. He dedicated years to research & develop True Body Intelligence (TBI), a comprehensive system that integrates & heals the physical, mental, emotional, & spiritual aspects of individuals.
With a client base ranging from sports to international politics, Christopher's practice in Los Angeles focuses on holistic well-being & longevity.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Stick with what works for you, whether it’s structure or flexibility
Understand your relationship with time & communicate it to those around you
Disregarding your time preferences can lower self-esteem; know your needs & share them
Use situations to gain freedom & avoid the common stress patterns others fall into
Just 10-15 minutes of positive stress management daily can be effective
Focus on being present; activities like cooking help maintain mindfulness
Higher self-esteem leads to positive stress management; lower self-esteem leans toward negative coping
Stress impact depends on interpretation, not the absolute level; the same event affects people differently
Get clear on what works for you in stress management & personal growth—always ask why
Self-understanding requires a deep or at least surface-level investigation
Every moment offers a choice: love or anger, excitement or anxiety, confidence or fear
Reducing accumulated lifetime stress lowers the impact of daily stress, making it easier to take heartfelt actions for your benefit
Episode Highlights
10:16 Impact of Stress Interpretation
17:51 Negative Stress Management Tools
21:58 Positive Stress Management Tools
29:46 Fool-proof Tips for Stress Management
32:44 How to use your stress to build courage
Links
Watch it on YouTube: https://youtu.be/mdl52X4xFQU
Full episode show notes: mindbodypeak.com/174
Connect with Nick on social media
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Nick

Sep 5, 2024 • 44min
#173 Eat More to Lose Weight, Rethinking “Essential” Nutrients (Omega-3s) | The Bioenergetic Diet | Jay Feldman @ Jay Feldman Wellness
Did you know you could lose weight by eating more carbs?
Join me with our guest, Jay Feldman as we delve into bioenergetic nutrition in part 2 of this 2-part podcast episode, exploring the advantages of a high-carb diet & the surprising drawbacks of omega-3 fatty acids.
Discover why efficient food-to-energy conversion is crucial & how to navigate your caloric needs seamlessly. Feldman also reveals his top tips on optimal carb sources and how fat intake can affect your metabolism in today’s episode on “Bioenergetic Health”.
Meet our guest
Jay is a health coach, independent health researcher, & the host of The Energy Balance Podcast. He has degrees in neuroscience & exercise physiology, & decided to forgo medical school after realizing that the conventional medical approach was not the solution to the health problems that so many of us face.
After working through various conventional & alternative health paradigms & trialing countless diets, Jay came across the idea that cellular energy is the foundation of our health. Embracing this discovery, he now uses the Energy Balance approach to help men & women around the world maximize their cellular energy, optimize their health, & achieve freedom from low-energy symptoms & chronic health issues.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
Adjusting to dietary changes takes time; going slow & steady helps avoid mistakes
Poor digestion of reintroduced carbs (bloating, gas) suggests the need for digestive adaptation, especially from a low-carb diet
Appetite reflects calorie needs: eat when hungry & avoid force-feeding when not
Increased activity, particularly with more muscle mass, raises fat needs, generally between 30–40% of total calories
At rest & during low-level activity, muscles predominantly use fat as fuel
Excessive fat reliance indicates a low metabolic state & can reduce metabolism, glucose burning, & thyroid function
Burning fuel at a higher rate leads to specific fat loss rather than merely accessing fat stores through suboptimal fuel
Increase carbs gradually to reduce stress, enhance thyroid & metabolism, & support healthy weight loss with minimal regain
Focus on starches that minimize anti-nutrients, & be aware that chicken & pork may contain fats from seed oils they consume
Omega-3s, often perceived as healthier than omega-6s, are even less stable due to additional double bonds & more susceptible to oxidative stress
The membrane pacemaker theory of aging suggests that the level of unsaturation in cell membranes is a major determinant of species longevity
Higher oxidative stress makes unsaturated fats, particularly omega-3s, more vulnerable to damage
Episode Highlights
03:34 How to Safely Transition From a Low-Carb Diet
14:41 The Path to Bioenergetic Nutrition
20:18 Omega-3 vs. Omega-6
41:31 Effective Supplementation
Links
Watch it on YouTube: https://youtu.be/QfPTMw6As0Y
Full episode show notes: mindbodypeak.com/173
Connect with Nick on social media
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Nick

Aug 29, 2024 • 1h 1min
#172 Shocking Dark Side of Keto, Intermittent Fasting & Caloric Restriction (& What to Do About It) | Jay Feldman @ Jay Feldman Wellness
Despite your best efforts to diet & shift your lifestyle, are you still lacking the results you hoped for? You may be unknowingly sabotaging yourself.
This episode challenges common myths about keto, intermittent fasting, and caloric restriction, highlighting the critical role of metabolic flexibility & the stress impacts of certain diets. Discover the transformative effects of techniques like Buteyko breathing & CO2 therapy, & learn how your individual genetics and lifestyle choices shape your health.
Meet our guest
Jay is a health coach, independent health researcher, & the host of The Energy Balance Podcast. He has degrees in neuroscience & exercise physiology, & decided to forgo medical school after realizing that the conventional medical approach was not the solution to the health problems that so many of us face.
After working through various conventional & alternative health paradigms & trialing countless diets, Jay came across the idea that cellular energy is the foundation of our health. Embracing this discovery, he now uses the Energy Balance approach to help men & women around the world maximize their cellular energy, optimize their health, & achieve freedom from low-energy symptoms & chronic health issues.
Thank you to our partners
Outliyr Biohacker’s Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear
Ultimate Health Optimization Deals: a roundup article of all the best current deals on technology, supplements, systems and more
Gain mental clarity, energy, motivation, and focus with the FREE Outliyr Nootropics Mini-Course
The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
Key takeaways
The idea that fat burns cleaner than glucose is a misconception; in many cases, glucose burns more efficiently
Short-term, ketones can boost metabolism, but long-term reliance on them can lower metabolic rates and promote fat storage
Ketones are primarily used by the brain; the rest of the body relies on fat
The brain, with its high metabolic needs, relies on glucose or ketones rather than fatty acids due to their more efficient energy production
Carbon dioxide (CO2) has antioxidant effects, helping protect against reactive oxygen and nitrogen species, and is beneficial in low-oxygen states
Chronic stress reduces CO2 levels, which can impact health
Episode Highlights
11:17 Everything You Need to Know About Balancing Stress & Energy
20:16 The Truth About Caloric Restriction & Fasting
34:14 Fats VS Carbs (The Ultimatum)
42:26 Controversial Health Practices for Longevity
47:47 Surprising Health Benefits of CO2 & Oxygen
Links
Watch it on YouTube: https://youtu.be/14i898-9DCY
Full episode show notes: mindbodypeak.com/172
Connect with Nick on social media
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Nick

Aug 22, 2024 • 1h 17min
#171 Why Your Supplements Make You Feel Worse (The Secret Hidden in Your Genetics) | Dr Tyler Panzner @ Holistic Genetic Health Optimization
Have you ever wondered why some health strategies & supplements work wonders for others but leave you feeling off-balance?
Discover how to tailor your health strategy with Dr. Tyler Panzer. Explore the effects of genetic mutations on sulfur sensitivity, histamine intolerance, and neurotransmitter production. Learn about the importance of individualized methylation support and bioharmonized nutrition to elevate your well-being and cognitive performance.
Meet our guest
Dr. Tyler Panzner is a Ph.D. scientist trained in pharmacology, cancer, neuroscience, and inflammation research who has had a lifelong passion for understanding how substances affect the body. While his scientific training spans well over a decade, his passion for genetics and personalized medicine started ~7 years ago and he's pursued his goal of personalizing vitamin, supplement, and lifestyle protocols for each individual.
He not only figures out exactly what your unique cells need, but also educates about which vitamins, supplements, and foods will clash with your unique biology.
Using this approach he believes that not only daily quality of life improves, but the risk for chronic diseases are greatly reduced. Dr. Panzner firmly believes that one's underlying genetic code dictates what the body needs to THRIVE. He's driven to genetically OPTIMIZE the human experience of life through his Holistic Genetic Health Optimization practice.
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Key takeaways
The significance of a gene mutation isn't determined by one mutation; genes can have tens of thousands of potential mutation sites
Science is never perfect; we’re always learning
Methylation is a foundational cellular process involved in turning genes on/off, making neurotransmitters, & producing glutathione
Lithium helps break down excess adrenaline, stabilizes mood, & supports neuroplasticity
Taking lithium orotate before bed can be life-changing for mood stabilization & reducing adrenaline
COMT & MAO genes are responsible for breaking down adrenaline, so you can't mentally lower adrenaline if these genes aren't functioning well
Food intolerances occur when the body can't digest certain proteins or components, usually a digestive, not an immune, issue
8 out of 10 kidney stones form from oxalate crystals
Episode Highlights
06:02 The Foundation of Genetics
16:37 How to Test Your Genetic Health
33:04 Why Supplements Aren't Working
36:35 The Best Methods to Optimize Your Genetics
47:51 The Gene that Affects Your Personality
Links
Watch it on YouTube: https://youtu.be/PrcC9L420PQ
Full episode show notes: mindbodypeak.com/171
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Nick