The Neuro Experience

What is VO2 Max? Did you know that your VO2 Max not only impacts your athletic performance but also serves as a key longevity indicator? This episode’s guest is Michael Joyner, M.D., a physician-researcher and one of the world’s leading experts on human performance and exercise physiology. Using humans as his model system, he has made major contributions to understanding muscle and skin blood flow, blood pressure regulation, and human athletic performance. In this episode, Mike and I discuss: The link between longevity and exercise How to measure and improve your VO2Max Whether obesity is genetic or environmental Chronic diseases and capillary dysfunction How to exercise for a longer, healthier life The prevalence of doping in elite sports The role of VO2 Max in longevity and healthspan [00:00] Introduction [02:20] The Correlation Between Exercise and Longevity [05:25] Thoughts on Modern Physical Activity Guidelines [07:44] Exercise, Health Benefits, and Mortality Risk [10:15] Healthy Blood Flow is Crucial For Overall Health [13:43] The Link Between VO2Max and Longevity [17:22] Why VO2 Max Declines with Age and What to Do About It [19:07] Zone 2 Training and Exercise Intensity [21:10] How to Improve Your VO2Max [25:16] Stroke Volume and Cardiac Remodelling For Longevity [27:34] Society’s Struggle with Obesity and Diabetes [29:50] Do Genes Affect Weight Loss and Weight Gain? [31:52] The Differences and Similarities Between Exercise and Physical Activity [34:02] The Anti-Inflammatory Effects of Exercise [35:58] Doping in Professional Sports [40:14] Practical Tips on Zone 2 Training and V02 Max For Longevity [41:33] Parting Thoughts *** The Neuro Athletics Newsletter: https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Michael Joyner, M.D., a physician-researcher and expert in exercise physiology, delves into the crucial role of VO2 Max in health and longevity. He explains how this measure not only affects athletic performance but also serves as a predictor of lifespan. The conversation covers whether obesity is more genetic or environmental and discusses practical strategies for improving VO2 Max. Joyner emphasizes the importance of exercise over medication and addresses the complexities surrounding obesity and chronic diseases for better overall health.

What are the benefits of regular, comprehensive bloodwork?This episode's guest is Dan Garner, the founder of Team Garner, Inc., which offers high-level personalized online training and nutritional coaching for world-class results. His coaching resume is second to none, having worked with dozens of professional athletes in 13 different sports. His clientele includes Superbowl champions, UFC title winners, NBA championship winners, Olympic gold medalists, hall-of-fame inductees, and Hollywood celebrities. In this episode, Dan and I discuss:- Why everyone should get some bloodwork done- Steps to a truly healthy lifestyle- How to work with your body for optimal health - Understanding the full movie of a person's psychology- The art and science of blood work- Whether chronic fatigue is a real thing- How to use lab work to understand humans on a cellular level.For the visual learners, come on over to YouTube for long form brain health related content  https://www.youtube.com/@LouisaNicolaWant to ask me a question? You can ask me anything I have covered on this podcast, go to : https://dexa.ai/louisaThe NACC course has certified over 500 coaches now. This is the state of the art human performance coaching company lead by a team of experts. Learn more about the NACC: https://www.neuroathletics.com.au/nacc Links and Resources:Dan’s website - Rapidhealthreport.comFollow Dan on Instagram: https://www.instagram.com/dangarnernutrition/Unlock the knowledge of trusted creators at: https://dexa.ai/Research report - Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damageThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices

Thomas DeLauer, a nutrition and business performance coach, discusses the keys to slowing down aging, habits for a longer, healthier life, hormetic stressors, calorie restriction, heat and cold therapies, and the role of FOX03 for longevity.

Thomas DeLauer, a nutrition and business performance coach with over 3.5 million YouTube subscribers, discusses longevity, key habits for a healthier life, hormetic stressors, calorie restriction, benefits of heat and cold therapies, and the role of FOX03 for longevity.

Charles Brenner is a leading Global expert in the biology, chemistry and Medicine of NAD the central Catalyst of metabolism he currently works at City of Hope in Los Angeles as professor and chair of the Department of diabetes and cancer metabolism. I'm intrigued by Charles' recent rebuttal to David Sinclair's thesis regarding longevity. "Surtuins are not conserved longevity genes" published in the Journal of Life metabolism in October 2022. In this episode Charles and I discuss this paper and his view on the science of longevity. We will expand on this while also discussing various other topics related to NAD, use cases for NR, metabolism and where influencers go wrong in the nutrition space. If you have any additional questions you would like answered in the future, let me know in the comments. Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at http://insidetracker.com/louisa Chapters: 00:00:00 - The Role of NAD in Metabolism and Living Things 00:11:18 - NAD and the De Novo Pathway 00:21:50 - The Composition of NAD and NR 00:33:07 - The Innate Immune Response and NAD Churning 00:44:08 - The Longevity of Naked Mole Rats and Humans 00:55:27 - The Myth of Sirtuin Genes and Longevity 01:06:26 - Reproducibility Issues and False Claims 01:17:32 - Targeting the Aging System 01:27:44 - The Uselessness of Age Tests 01:38:26 - Q&A on Twitter Optimise your hydration and get a free sample pack of electrolytes at http://drinklmnt.com/neuro Connect with Dr Charles Brenner: - Twitter: https://twitter.com/CharlesMBrenner - Website: https://www.brennerlab.net/ The best way to support the show is to use the products and services offered by our sponsors. Connect with Dr Charles Brenner: - Twitter: https://twitter.com/CharlesMBrenner - Website: https://www.brennerlab.net/ *** The Neuro Athletics Newsletter: https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

On the quest to understand the aging process and how to slow it down, the world of longevity research is anything but straightforward. Scientists have long been exploring a variety of pathways that may influence lifespan, cellular health, and overall well-being. Two prominent figures in the longevity research space, Dr. Charles Brenner and Dr. David Sinclair, offer contrasting views on some key aspects of aging, such as the role of NAD and sirtuins.In this episode Charles and I discuss this paper and his view on the science of longevity. We will expand on this while also discussing various other topics related to NAD, use cases for NR, metabolism and where influencers go wrong in the nutrition space.If you have any additional questions you would like answered in the future, let me know in the comments.Watch the episode on YouTube: https://youtu.be/Kbnv6OE8o30Write a question on Spotify: https://tinyurl.com/bdz259u4Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at http://insidetracker.com/louisaOptimise your hydration and get a free sample pack of electrolytes at http://drinklmnt.com/neuroConnect with Dr Charles Brenner:- Twitter: https://twitter.com/CharlesMBrenner- Website: https://www.brennerlab.net/The best way to support the show is to use the products and services offered by our sponsors.Connect with Dr Charles Brenner:- Twitter: https://twitter.com/CharlesMBrenner- Website: https://www.brennerlab.net/The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices

Today, I dive deep into the world of bloodwork, DNA, and fitness tracking with none other than Dr. Renee Deehan, Vice President of Science and Artificial Intelligence at Inside Tracker. Get 20% off you next bloodwork CODE: LOUISA20 https://info.insidetracker.com/louisa Chapters: 00:00:00 - Wearable Data and its Benefits 00:05:39 - Lowering LDL Cholesterol Levels 00:11:29 - Personalized Health Optimization 00:17:08 - The Importance of Blood Work and DNA in Health Assessments 00:22:39 - Managing Stress and Cold Plunges 00:28:17 - Predictive analytics in health and medicine 00:33:49 - Drawbacks of Utilizing AI in Healthcare 00:39:20 - Women's Representation in Pharmacokinetic Studies 00:44:27 - The Role of AI in Making Blood Work More Accessible We cover: - Intro to bloodwork, biomarkers, and Inside Tracker's role. - AI's impact on bloodwork analysis: benefits and challenges. - AI's role in analyzing LDL cholesterol for early cardiovascular disease detection. - Emerging AI innovations for personalized bloodwork in preventative healthcare. - Ethical considerations in AI for early disease detection. - AI's potential to democratize bloodwork understanding, empowering public health. *** The Neuro Athletics Newsletter: https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Renee Deehan, VP of Science and AI at Inside Tracker, discusses how AI is revolutionizing bloodwork analysis, early disease detection, and personalized recommendations. They explore the importance of bloodwork and DNA analysis in understanding factors like cardiovascular disease and dementia. They also touch on the potential of image description technology and its impact on education.

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