In this episode, my guest is Peter Attia, M.D. He completed his medical and advanced training at Stanford University School of Medicine, Johns Hopkins School of Medicine and the National Institutes of Health (NIH). Dr. Attia is host of the health and medicine podcast, The Drive, and the author of a new book, “Outlive: The Science & Art of Longevity,” which examines disease prevention and healthy aging, including emotional health. He explains the leading causes of death worldwide and how to measure one’s risk of death and mitigate each risk factor. Dr. Attia shares how, in addition to blood-based markers of lipids and hormones, there are behavioral measures and interventions, and key aspects of emotional health (i.e., relationships, emotional stability, purpose, etc.) that fundamentally impact our physical health and longevity, and how to assess and adjust our emotional health. This episode is rich with actionable information related to disease screening and biomarker testing, nutritional, exercise, behavior and prescription-based tools that area useful to all people regardless of age, male or female, and that can significantly improve vitality, health and lifespan.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1: https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanlabWaking Up: https://wakingup.com/hubermanMomentous: https://livemomentous.com/hubermanTimestamps(00:00:00) Dr. Peter Attia(00:03:39) Sponsor: LMNT(00:07:34) Lifespan vs. Healthspan(00:10:54) “4 Horseman of Death”, Diseases of Atherosclerosis(00:14:44) Tool: Hypertension & Stroke, Blood Pressure Testing (00:23:14) Preventing Atherosclerosis, Smoking & Vaping, Pollution(00:28:33) Sponsor: AG1(00:33:29) Cholesterol, ApoB(00:42:21) Cholesterol Levels, LDL & ApoB Testing(00:49:29) ApoB Levels & Atherosclerosis, Causality(01:01:06) ApoB Reduction, Insulin Resistance, Statins, Ezetimibe, PCSK9 Inhibitors(01:12:30) Monitoring ApoB(01:18:30) Reducing Blood Pressure, Exercise & Sleep(01:20:50) High Blood Pressure & Kidneys(01:23:11) Alcohol, Sleep & Disease Risk(01:31:21) Cancer & Cancer Risks: Genetics, Smoking & Obesity(01:39:47) Cancer Screening & Survival(01:44:17) Radiation Risks, CT & PET Scans(01:48:48) Environmental Carcinogens(01:52:11) Genetic & Whole-Body MRI Screening, Colonoscopy(01:58:47) Neurodegenerative Diseases, Alzheimer’s Disease, ApoE(02:08:08) Alzheimer’s Disease & Amyloid(02:13:58) Interventions for Brain Health, Traumatic Brain Injury (TBI)(02:21:26) Accidental Death, “Deaths of Despair”, Fentanyl Crisis(02:31:20) Fall Risk & Stability, 4 Pillars of Strength Training(02:41:05) Emotional Health(02:53:45) Mortality & Preserving Relationship Quality(03:02:20) Relationships vs. Outcomes, Deconstructing Emotions(03:09:34) Treatment Centers, Emotional Processing & Recovery(03:16:34) Tool: Inner Monologue & Anger, Redirecting Self-Talk(03:27:37) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterDisclaimer

Dr. Peter Attia, founder of Early Medical, discusses longevity, optimizing protein, alcohol rules, lessons from glucose monitoring with CGMs, boosting VO2 max, preventing Alzheimer's, early cancer detection, using DEXA scans, and nature's longevity drug.

My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health. For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1: https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanlabWaking Up: https://wakingup.com/hubermanMomentous: https://livemomentous.com/hubermanTimestamps(00:00:00) Assessing Health Status & Improving Vitality (00:03:07) Sponsors: AG1, LMNT(00:07:29) Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease” (00:11:51) Healthspan: Functional Testing, Cognitive & Emotional States (00:13:59) Blood Testing: Best Frequency (00:16:01) DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis (00:22:33) Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids (00:29:24) Osteopenia & Osteoporosis Diagnosis, Strength Training(00:29:52) Sponsor: AG1(00:32:16) Back-casting: Defining Your “Marginal Decade” (00:38:31) All-Cause Mortality: Smoking, Strength, VO2 max (00:44:43) Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals(00:49:24) Importance of Exercise, Brain Health, MET hours (00:55:23) Nicotine & Cognitive Focus(01:03:12) Menstruation, PMS & Menopause (01:10:10) Hormone Replacement Therapy, Menopause & Breast Cancer Risk(01:22:06) Estrogen, Progesterone & Testosterone Therapies in Women(01:26:35) Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin(01:37:23) Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG(01:47:46) Fadogia Agrestis, Supplements, Rapamycin (01:52:06) Testosterone Replacement Therapy & Fertility (01:59:26) Total Testosterone vs. Free Testosterone(02:02:51) Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B(02:17:42) Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions (02:25:15) Cardiovascular Disease, Age & Disease Risk (02:28:53) Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation (02:37:40) Metabolomics & Exercise (02:40:44) GLP-1 & Weight Loss (02:47:06) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab ClipsDisclaimer

Dr. Peter Attia discusses health, longevity, and fitness tips, including the high costs of American healthcare, optimizing cognition, strategies to prevent cognitive decline and enhance brain health, the complexities of testosterone replacement therapy, and the importance of emotional well-being and self-talk transformation. The podcast also covers topics such as mental health therapy, muscle-building strategies, magnesium and creatine supplementation, sleep quality optimization, and controversial health issues like processed foods and sun exposure.

Dr. Peter Attia, a physician trained at Stanford and Johns Hopkins, focuses on enhancing healthspan and lifespan. In this conversation, he explores the NAD pathway's links to aging and evaluates popular supplements like NMN and NR for longevity. The dialogue dives into how lifestyle choices like sleep, nutrition, and exercise play vital roles in health, as well as whether biological age tests are reliable indicators of aging. Listeners will also discover the complexities behind supplements and their real efficacy in extending lifespan.

Dr. Peter Attia, a physician focusing on healthspan and lifespan, joins the podcast to discuss the effects of light and dark on mental health and treatments for cancer. They explore papers on bright light exposure improving mental health, immunotherapy treatments for cancer, and the safety of low-calorie sweeteners. The podcast offers science-supported ways to improve mental health and lifespan for listeners.

Dr. Peter Attia, highly respected expert in preventive medicine, talks about longevity and cardiovascular health. They discuss defining cardiovascular disease, coronary plaque and fatality risk, cholesterol, ApoB predictions, genetics, diet, statins, statin side effects, training in zone 2, statins and neurodegenerative diseases, and cholesterol synthesis in the brain. They also touch on statin alternatives, ubiquinol supplements for muscle soreness, cholesterol-lowering drugs, and modifiable risk factors for cancer.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this special episode filmed live in front of readers of Outlive, Peter answers questions revolving around his concept of the centenarian decathlon. He starts by defining the “marginal decade” and how that shapes his training for the events and activities that make up his personal centenarian decathlon. Peter explains how he coaches patients through the challenges of customizing their own list and building out a training plan, including how to set fitness goals early in life in preparation for the marginal decade. From there, he dives into training within the four pillars (zone 2, VO2 max, stability, and strength), including the minimum effective dose, how to split your time, his personal protocols, and other considerations. Additionally, he touches on bone mineral density, female-specific considerations, working through injuries, and the profound impact training can have on the overall quality of life. We discuss: The best interventions for longevity [2:15]; The marginal decade and the centenarian decathlon [4:45]; Peter’s personal list of events for his “centenarian decathlon” and how he helps patients create their own list [8:00]; Determining your fitness goals early in life in preparation for the marginal decade, metrics to track, and more [15:00]; How does playing sports like tennis, basketball, or golf fit into training for the centenarian decathlon? [24:15]; Training within the four pillars: minimum effect dose, how to split your time, and other considerations [27:45]; Advice for the older person and why it’s never too late to start [33:45]; Bone mineral density and other female-specific concerns and considerations [36:15]; Training advice for those with minimal access to a gym or equipment [39:30]; Injuries: prevention and working through existing conditions [41:00]; Cardiorespiratory training: how to split time between zone 2 and VO2 max training, and different modalities for a true zone 2 workout [44:15]; VO2 max training: modalities, Peter’s protocol, and how to monitor progress [54:45]; The profound impact training can have on the overall quality of life [58:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Dr Peter Attia is a physician, longevity expert, podcaster and an author.Working out what to actually do if we want to maximise our health and lifespan has become an increasingly difficult task. There are an unlimited number of wellness approaches available, but thankfully Dr Attia has spent his career assessing the most important strategies we all should be focussing on for fitness and longevity.Expect to learn how to best increase your chances of living longer, the role of fasting in longevity, the most important metric that predicts a long healthy life, the longterm effects of vaping and alcohol, how you can prevent cognitive decline, the vital signs that everyone overlooks, how to design a science-backed weekly workout regime and much more...Extra Stuff:Buy Outlive - https://amzn.to/413jYwH Check out Peter's website - https://peterattiamd.com/ Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/To support me on Patreon (thank you): https://www.patreon.com/modernwisdom-Get in touch.Instagram: https://www.instagram.com/chriswillxTwitter: https://www.twitter.com/chriswillxYouTube: https://www.youtube.com/modernwisdompodcastEmail: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices

Peter Attia, a medical doctor specializing in longevity, discusses the importance of starting exercise for aging individuals over 50. He covers the decline in muscle mass and VO2 max with age, providing practical advice on structuring exercise programs for older adults. The conversation emphasizes setting realistic goals, improving aerobic capacity through consistency, and incorporating resistance training for muscle building.