Dr. David Perlmutter, a board-certified neurologist and nutrition expert, dives into the crucial connections between diet, uric acid, and brain health. He highlights how hidden sugars can sabotage even the healthiest meals, emphasizing the importance of knowing your uric acid levels. The discussion also touches on the gut-brain relationship and how dietary changes can prevent diseases like diabetes and dementia. Perlmutter advocates for personalized diet plans and a mindful approach to eating, aiming to combat modern health challenges.

In this insightful discussion, Dr. David Perlmutter, a renowned neurologist and bestselling author focused on brain health, shares critical insights on preventing and reversing Alzheimer's disease. He explores the link between metabolism and cognitive decline, emphasizing the role of mitochondrial health. Listeners learn how dietary choices, like fructose consumption, and metabolic innovations like GLP-1 drugs can significantly impact brain function. Dr. Perlmutter also highlights the importance of community support and personal experiences in navigating the complexities of Alzheimer's.

In this engaging discussion, David Perlmutter, a renowned neurologist and bestselling author, uncovers the overlooked importance of uric acid in chronic diseases like obesity and diabetes. He explains how our modern food environment clashes with our biological needs, emphasizing how even slightly elevated uric acid can be detrimental. The conversation also highlights the critical connections between nutrition, brain health, and lifestyle choices, advocating for preventative health measures and mindful dietary habits to combat metabolic disorders.

Dr. David Perlmutter discusses silent symptoms of dementia and brain decline, emphasizing early lifestyle changes for brain health. Topics include metabolic health indicators, oral microbiome impact on neurodegenerative diseases, Alzheimer's prevention through lifestyle choices, optimizing brain health with diverse activities, importance of glutathione in detoxification, and the connection between long-distance running and atrial fibrillation.

In this engaging discussion, Dr. David Perlmutter, a renowned neurologist and bestselling author, uncovers the surprising role of uric acid in our health. He explains how high fructose consumption dramatically raises uric acid levels, linking it to obesity and diabetes. Delving into dietary choices, he highlights the importance of whole fruits over juices and advocates for healthier alternatives to sugar. With insights on sleep quality and chronic disease, Perlmutter urges a reconsideration of uric acid as a vital metabolic marker, encouraging smarter nutrition for better health outcomes.

Levels Chief Medical Officer, Dr. Casey Means, chatted with our advisor, Dr. David Perlmutter on the discovery of how the elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases, and one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, fatty liver disease, and more. Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl They also covered: The several mechanisms of how uric acid causes cellular dysfunction and insulin resistance, including oxidative stress, inflammation, and even preventing insulin from getting out of the blood stream effectively. The evolutionary reasons why the metabolic dysfunction and weight gain caused by uric acid would have benefitted us historically in terms of low access to food and water, by letting us more easily pack on weight and raise blood pressure. And how we now live in an evolutionary-environmental mismatch where this survival mechanism is now hurting us in the face of caloric abundance. The different dietary and environmental factors that generate uric acid, including fructose, purine rich foods and umami foods, dehydration, alcohol, and more. The optimal levels for uric acid. How uric acid impairs our hunger signals, drives us to eat, and even promotes risk taking behavior. We talked about how to reverse high uric acid levels as a way to unlock optimal health. Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health. Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health. (04:23) - More than just gout (06:17) - A causative role (08:54) - The number one cause of death (16:35) - Evolutionary environmental mismatch (18:08) - High fructose corn syrup (23:39) - The dangers of uric acid (24:49) - Uric acid and dementia (31:44) - Too much fructose (42:43) - Erectile dysfunction and cardiovascular risk (01:04:29) - No need to eat sugar Transcripts & Show Notes

Dr. David Perlmutter, a renowned neurologist, challenges conventional beliefs about Alzheimer's, emphasizing it's more than just genetics—metabolic health is key. He reveals that brain degeneration can start 20 to 30 years before symptoms show. Using engaging analogies, he compares the brain's energy needs to a car engine and highlights the critical role of mitochondria. Dr. Perlmutter advocates for proactive health management, stressing that lifestyle choices significantly impact cognitive health and that many risk factors are within our control.

The elevation of uric acid in the body is a causative mechanism in the development of metabolic diseases and contributes to weight gain and fat production. Uric acid is one of the key links between obesity, diabetes, heart disease, neurologic diseases like dementia, ADHD, non-alcoholic fatty liver disease, and more. Dr. David Perlmutter talks with Dr. Casey Means about why we have excess uric acid, what foods cause uric acid production, and what simple steps we can take to lower our uric acid levels to be optimal. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry.Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠They also cover: How uric acid causes cellular dysfunction and insulin resistance, including oxidative stress, and inflammation, and even prevents insulin from getting out of the bloodstream effectively. Why uric acid would have benefitted us evolutionarily in terms of low access to food and water by letting us more easily pack on weight and raise blood pressure—but how that fights against us today because we now live in an evolutionary-environmental mismatch where this survival mechanism hurts us in the face of caloric abundance. The different dietary and environmental factors that generate uric acid, including fructose, purine-rich foods and umami foods, dehydration, alcohol, and more. How uric acid impairs our hunger signals, drives us to eat, and even promotes risk-taking behavior. How to reverse high uric acid levels as a way to unlock optimal health.🎙 What Dr. David Perlmutter & Dr. Casey Means discuss:(00:00) - Intro(03:12) - More than just gout(05:06) - A causative role(07:44) - The number one cause of death(15:24) - Evolutionary environmental mismatch(16:58) - High fructose corn syrup(22:27) - The dangers of uric acid(23:38) - Uric acid and dementia(30:33) - Too much fructose(41:32) - Erectile dysfunction and cardiovascular risk(01:03:17) - No need to eat sugarTranscripts & Show notes🔗 Helpful links:Watch the conversation: https://youtube.com/watch?v=QZ6jPCcFNa8Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1📲 Connect:Connect with Dr. Casey Means on Instagram: https://instagram.com/DrCaseysKitchenConnect with Casey on Twitter: https://instagram.com/DrCaseysKitchenConnect with David Perlmutter, MD on Instagram: https://instagram.com/davidperlmutterConnect with David on Twitter: https://twitter.com/DavidPerlmutterConnect with David on LinkedIn: https://linkedin.com/in/david-perlmutter-md-6a38b930

Dr. David Perlmutter, a neurologist and bestselling author, dives into the critical role of uric acid in our metabolic health. He explains how high levels of uric acid can lead to fat storage and chronic diseases. With insights from his book 'Drop Acid,' he emphasizes the need for dietary awareness, focusing on sources like fructose and purines. Listeners learn about innovative monitoring solutions and the significance of seasonal eating, supplements, and lifestyle changes to manage uric acid for better health.

In this discussion, Dr. David Perlmutter, a board-certified neurologist and bestselling author, dives into how diet shapes our behavior and risks of diseases like Alzheimer's. He explains the science behind uric acid and its crucial role in weight management and blood sugar control. The conversation touches on sugar addiction, the impact of childbirth methods on long-term health, and personalized dietary strategies. Listeners gain insights into optimizing their brain health and fighting cognitive decline through nutrition.