Age Less / Live More

660: Why We Eat Too Much with Andrew Jenkinson

Feb 19, 2025
Andrew Jenkinson, a bariatric surgeon and author of *Why We Eat (Too Much)*, sheds light on the complexities of hunger and obesity. He explains how hormonal imbalances, particularly with insulin and leptin, lead to overeating. The conversation highlights the rise of GLP-1 drugs in weight management and contrasts them with surgical options. Jenkinson also discusses the critical role of Omega-3 fatty acids and the importance of personalized nutrition for effective weight control. Tune in for valuable insights into tackling the roots of hunger!
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INSIGHT

Leptin Resistance: The Root of Obesity

  • Obesity is driven by leptin resistance, not character flaws.
  • Leptin resistance disrupts appetite control, leading to increased hunger and decreased metabolism.
INSIGHT

Leptin and Insulin: A Hormonal Imbalance

  • The hormone leptin signals satiety to the hypothalamus, regulating energy storage.
  • High insulin levels, common in modern diets, can interfere with leptin signaling, leading to leptin resistance.
ANECDOTE

Satiety Signals: A Child vs. Adult Perspective

  • Lucas Rockwood's son naturally regulates his candy intake, demonstrating inherent satiety signals.
  • Rockwood himself lacks this brake pedal for simple carbohydrates, highlighting the impact of age and hormonal dysregulation.
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