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Age Less / Live More

660: Why We Eat Too Much with Andrew Jenkinson

Feb 19, 2025
Andrew Jenkinson, a bariatric surgeon and author of *Why We Eat (Too Much)*, sheds light on the complexities of hunger and obesity. He explains how hormonal imbalances, particularly with insulin and leptin, lead to overeating. The conversation highlights the rise of GLP-1 drugs in weight management and contrasts them with surgical options. Jenkinson also discusses the critical role of Omega-3 fatty acids and the importance of personalized nutrition for effective weight control. Tune in for valuable insights into tackling the roots of hunger!
47:38

Podcast summary created with Snipd AI

Quick takeaways

  • Leptin resistance, driven by modern diets rich in sugar and refined carbohydrates, significantly impacts hunger regulation and weight management.
  • Balancing omega-3 and omega-6 fatty acids is crucial for improving insulin sensitivity and mitigating metabolic issues related to obesity.

Deep dives

Understanding Hunger and Satiety Signals

The episode examines the complexities of hunger and satiety signals, particularly focusing on the role of the hormone leptin. Leptin, which is secreted by fat cells, communicates with the hypothalamus in the brain to regulate energy balance and appetite. However, modern dietary patterns, characterized by high sugar and refined carbohydrate intake, can lead to leptin resistance, where the brain no longer responds effectively to leptin signals. As a result, individuals may experience increased hunger and overeating, making weight management significantly more challenging.

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