The Genius Life 378: How to Build an Alzheimer's-Resistant Brain and Reduce Cognitive Decline | Lisa Mosconi, PhD
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Mar 13, 2024 
Neuroscientist Lisa Mosconi discusses strategies to build an Alzheimer's-resistant brain, including lifestyle adjustments and water quality. The podcast explores the impact of nutrition and lifestyle choices on brain health and emphasizes the importance of cognitive reserve through exercise, diet, sleep, and intellectual challenges. It also delves into the role of menopause in brain health, addressing symptoms, hormone replacement therapy controversies, and the need for evidence-based approaches.
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Triage Whole-Person Health
- Manage existing medical conditions like heart disease, diabetes, obesity, and thyroid issues to protect your brain health.
- Target lifestyle modifications and collaborate across specialties rather than treating organs in isolation.
A Large Portion Of Dementia Is Preventable
- Conservative population estimates suggest roughly 20–60% of dementia cases are preventable, with many analyses centering near 40%.
- As more lifestyle-linked research accumulates, the preventable proportion will likely rise.
Stretch Your Cognitive Muscles
- Build cognitive reserve by continuously learning and layering cognitive challenges to form new neural connections.
- Treat intellectual training like exercise: stretch your brain to strengthen networks and resilience.