This Podcast Will Kill You

Ep 2 Skin in the Game, Horse in the Race

Nov 7, 2017
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INSIGHT

Leprosy Needs Prolonged Contact And Has Long Incubation

  • Leprosy spreads through respiratory droplets and requires prolonged close contact plus susceptible immune response.
  • Incubation ranges 1–20 years (average ~5 years), making exposure source and diagnosis very difficult.
INSIGHT

Disease Form Depends On Host Immunity Not Strain

  • Clinical forms (tuberculoid, lepromatous, borderline) depend on host immune response, not bacterial strain.
  • About 95% of humans are naturally resistant, so only ~5% become symptomatic after exposure.
ANECDOTE

Historical Rituals Declared Lepers Dead To Society

  • Historically people with skin conditions were publicly shamed: cloaks, bells, forced grave rituals, dissolved marriages, and exile to lazar houses.
  • Priests often diagnosed leprosy, so many non-leprosy skin diseases were misclassified and punished.
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