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Sigma Nutrition Radio
Stephan Guyenet, PhD – Overeating, Fat Mass Regulation & Energy Homeostasis
May 5, 2015
Stephan Guyenet, PhD discusses fat mass regulation via energy homeostasis systems, overeating, and the difference between homeostatic and non-homeostatic eating. They explore the interplay between satiety, energy homeostasis, and hedonic systems in regulating food intake. They discuss the challenges of weight maintenance and strategies for weight loss, including metabolic adaptations and controlling the food environment.
01:05:02
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Quick takeaways
- Gradual weight regain after weight loss is common due to the brain's starvation response.
- Humans are hardwired to seek high calorie foods to optimize energy intake.
Deep dives
Maintaining weight loss is more difficult than losing weight.
Many people find it easier to lose weight than to maintain that weight loss. Studies show that gradually regaining weight over a few years is common after weight loss. This may be due to the brain responding to weight loss by activating a starvation response, increasing hunger and reducing energy expenditure.
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