Metabolic Mind

Are We Using GLP-1 Medications All Wrong? with Dr. Ben Bikman

Jul 14, 2025
Dr. Ben Bikman, a metabolic health researcher and professor at BYU, discusses innovative ways to use GLP-1 medications like Ozempic and Wegovy. He suggests microdosing these drugs to curb cravings instead of high doses long-term. Bikman emphasizes the benefits of low-carb diets and the importance of habit changes for sustainable health. This approach aims to preserve muscle while facilitating fat loss, rethinking traditional obesity management as a temporary solution rather than a lifelong dependency on medication.
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INSIGHT

Concerns About Current GLP-1 Use

  • GLP-1 drugs are too effective and have significant side effects like muscle loss and mood disorders.
  • These consequences suggest the current high-dose, long-term use might be harmful.
INSIGHT

Lean Mass Loss and Diminishing Returns

  • Lean mass loss with GLP-1 drugs resembles loss from caloric restriction or gastric bypass.
  • Diminishing drug effects likely arise from biology's resistance to prolonged high signaling.
INSIGHT

GLP-1 and Carbohydrate Craving

  • Humans crave carbohydrates intensely, not fats or proteins.
  • Dysfunctional GLP-1 responses fail to stop carb cravings, potentially driving obesity.
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