Metabolic Mind

Bret Scher
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Jan 12, 2026 • 42min

Inside Metabolic Collective: Fueling Change in Mental Health

The science of metabolic psychiatry is advancing, but the movement behind it is just getting started. In this episode, Dr. Bret Scher sits down with Natasha Smikles and Eddie Rodriguez from Metabolic Collective, a new nonprofit working to build an international advocacy network for ketogenic and metabolic therapies.Their goal: accelerate awareness, adoption, and support for metabolic interventions in mental health.They cover:The personal journeys that led Natasha and Eddie to metabolic therapyWhy lived experience is such a powerful driver of changeWhy Metabolic Collective was created, and who it’s forHow Metabolic Collective is organizing community-led advocacy and educationWhat tools, resources, and events are available to help you get involvedHow to support others, start a local group, or bring metabolic psychiatry into your communityMetabolic psychiatry is growing, and movements like this are helping close the gap between research and real-world impact. From mental health challenges to neurological disorders, the Metabolic Collective hopes to spread the word about metabolic therapies and empower patients with alternative options to standard of care.👉Learn more about the Metabolic Collective at https://metaboliccollective.org. 👉Read the Metabolic Collective case for support at https://metaboliccollective.org/case-for-support/.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatry🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Experts Featured:Natasha Smiklesnatasha@metaboliccollective.orghttps://www.instagram.com/natasha.smikles/https://x.com/NatashaSmikleshttps://www.linkedin.com/in/natasha-smikles-93753523a/Eddie Rodriguezhttps://www.instagram.com/brainheal_th_/?hl=enhttps://www.youtube.com/@BrainHeal_th_https://x.com/BrainHealth919Resources Mentioned:https://metaboliccollective.org/https://metaboliccollective.org/case-for-support/https://www.metabolicmind.org/thinksmart/https://www.facebook.com/groups/metaboliccollective/https://x.com/metcollectiveFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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Dec 29, 2025 • 28min

Q&A: Caffeine, Carnivore, Meds, and Ketones—What’s Helping or Hurting Your Mental Health?

Is caffeine sabotaging your mental health progress? Should you try a carnivore diet if keto isn't working? What if your meds lower ketones?In this new Metabolic Mailbag episode, Dr. Georgia Ede joins Dr. Bret Scher to answer your most pressing questions about metabolic therapies, mental health, and more.Together, they dive into nuanced, evidence-informed conversations about:The real impact of caffeine on mood, sleep, and ketosisWhether the carnivore diet is “too high” in proteinWhy some people see mental health improvements on carnivore when a ketogenic diet hasn’t workedWhat to do when medications interfere with ketone levels, and why deprescription must be done safely and strategicallyAnd moreMetabolic psychiatry is a promising frontier, and we’re here to empower individuals navigating serious mental illness with tools and knowledge rooted in science, compassion, and real-world experience.🔎Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.🔔 Subscribe to Metabolic Mind and join the growing community exploring metabolic therapies for mental health: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Change Your Diet, Change Your Mind by Dr. Georgia Edehttps://www.amazon.com/Change-Your-Diet-Mind-Powerful/dp/1538739070 Taper Down Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 1)https://www.youtube.com/watch?v=RVMvi-vU5E8 Go Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 2) https://www.youtube.com/watch?v=rUdXDG8uKUY Keto and Psych Meds Topic Pagehttps://www.metabolicmind.org/resources/topics/keto-and-psych-meds/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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Dec 22, 2025 • 39min

Rethinking Serotonin And Depression: What SSRIs Really Do & What May Work Better

Chris Masterjohn, a biochemist and nutrition scientist, dives deep into the complexities of serotonin and SSRIs. He challenges the notion that SSRIs are solely mood boosters, revealing their potential disruption of mitochondrial function. Masterjohn emphasizes the role of brain energy metabolism and argues that exercise and nutrition can outperform medication in treating depression. He also highlights the benefits of morning sunlight on serotonin levels and mitochondrial activity, suggesting new pathways for understanding and addressing mental health.
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Dec 15, 2025 • 31min

Q&A: Healthy Fats, Alcohol, Perimenopause, & More

Is carb-cycling okay on a ketogenic diet? What about high histamine foods?In this episode of Metabolic Mailbag, Dr. Bret Scher and Dr. Georgia Ede answers questions on everything from the best sources of dietary fat to how to handle anxiety, perimenopause, and alcohol while maintaining ketosis.They unpack how to build a nutrient-dense, brain-supportive ketogenic diet using whole foods, why “keto-friendly” processed products can sometimes derail progress, and when supplements might be beneficial. You’ll also learn why histamine sensitivity, caffeine, or cycling in and out of ketosis can affect mood, and how to troubleshoot each.This conversation covers:Why a whole food ketogenic diet can be ideal for mental healthHow to identify the best fat sources and avoid “factory fats”Ketogenic dieting for women’s healthWhy anxiety can worsen mid-journey, and how to adaptThe truth about alcohol, carb cycling, and ketosisIf you’re exploring ketogenic therapy for mental or metabolic health, this episode offers practical, science-based guidance to help you refine and personalize your approach.🔎 Have questions about ketogenic diets or how to apply ketogenic therapy effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉Stay up to date with the latest, news, insights, and research on metabolic psychiatry by subscribing to Metabolic Mind: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Dr. Bret Scher’s Carb Cycling Video: https://www.youtube.com/watch?v=b5bUc7TbS6oDr Madison Kackley: Keto for Women https://www.youtube.com/watch?v=IQ8aGNwGB9cFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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Dec 8, 2025 • 34min

Could Stress Be The Hidden Driver of Mental Illness?

D. Parker Kelley, a postdoctoral fellow specializing in trauma and mitochondrial psychobiology, joins the conversation to explore the relationship between chronic stress and mental illness. He introduces the Allostatic Triage Model, which suggests that stress prompts the brain to prioritize limited energy resources, potentially leading to psychiatric symptoms. Kelley discusses how stress impacts metabolism, the significance of predictability in resilience, and how dietary choices and even psychedelics might aid brain energy regulation.
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Dec 2, 2025 • 6min

New Alzheimer’s Trial Reveals Surprising Insight on Brain Health

A recent trial by Novo Nordisk revealed that GLP-1 medications failed to significantly slow Alzheimer’s progression. Dr. Bret Scher discusses why these metabolic fixes may not be enough when it comes to neuronal damage. He highlights ketones as a promising alternative brain fuel and shares early research showing ketogenic therapy's potential benefits for cognition. The discussion emphasizes the need for more funding for nutritional therapies and a combined approach focusing on brain energy support and inflammation reduction.
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Nov 24, 2025 • 37min

The Data Is In: Reversing Metabolic Disease Is Possible

Dr. Adam Wolfberg, Chief Medical Officer at Virta Health and former OBGYN, shares groundbreaking insights on reversing metabolic diseases. He discusses how carbohydrate-reduced and ketogenic diets can lead to significant health improvements, including a 56% lower risk of heart attacks and strokes. They explore the shift from managing chronic conditions to pursuing reversal, highlighting Virta’s success across various socioeconomic backgrounds. Wolfberg emphasizes the importance of personalized care and the economic benefits of a value-based healthcare model.
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Nov 17, 2025 • 35min

Metabolic Mailbag: Ketone Plateaus, Sleep Issues, Fat Intake, and More

Ever wonder why your ketone levels dip after a few months on a ketogenic diet? Or how exogenous ketones compare to ketones produced naturally?In this Metabolic Mailbag episode, Dr. Bret Scher and Dr. Georgia Ede unpack the latest round of keto questions asked by the community.💡 You’ll learn:What lower ketone levels actually meanHow to know if you need to raise your ketonesHow exogenous ketones compare to ketones produced by the bodyHow to troubleshoot keto-induced insomniaThe difference between total and net carbs and which one you should be paying attention toHow much fat you should eat on a ketogenic dietIf you’re exploring ketogenic therapy for mental or metabolic health, this episode offers expert insights on the most common keto questions to help you feel confident in your journey.🎥Still have questions about ketogenic therapy and metabolic health? Check out our previous mailbag episodes, which cover a range of commonly asked questions: https://www.youtube.com/watch?v=3m6Fm0nXaMQ👉Do you have a question about ketogenic therapy or metabolic psychiatry? Submit your question to our team here: metabolicmind.org/questions#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd?ref_src=twsrc^google|twcamp^serp|twgr^authorhttps://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Treatment Resistant Depression SeriesPart 1: https://youtu.be/q7jg6wlD6gYPart 2: https://youtu.be/ay4RjudumHwPart 3: https://youtu.be/nGTx-i42yFEMetabolic Psychiatry for Non-Prescribershttps://ally-academy-nw.ce-go.com/metabolic-psychiatry-for-non-prescribers-23-07-2025-503Keto Mojo Macronutrient Calculatorhttps://keto-mojo.com/mymojomacros-keto-macro-calculator/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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Nov 10, 2025 • 58min

Why Setbacks Can Happen with Ketogenic Therapy for Mental Illness — and How to Respond

Dr. Georgia Ede, a seasoned psychiatrist specializing in ketogenic therapies, joins patient advocate Matt Baszucki and content creator Lauren Kennedy West, who shares her journey with schizoaffective disorder. They dive into the non-linear path of healing, tackling the emotional rollercoaster of tapering medications. Insights include managing variable ketone levels, stigma around dietary choices, and the importance of support systems. They also discuss how setbacks can drive personal growth, encouraging listeners to embrace challenges on the road to mental health.
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Nov 3, 2025 • 41min

A UC Davis Scientist on Why Meat Isn’t the Climate Villain

Is the diet being promoted to “save the planet” actually based on environmental data?In this eye-opening interview, Dr. Frank Mitloehner, air quality specialist and director of the CLEAR Center at UC Davis, unpacks the claims behind the EAT-Lancet 2.0 report, particularly the idea that cutting animal-sourced foods will drastically reduce environmental harm. Despite widespread media framing it as a climate solution, Dr. Mitloehner reveals that the Planetary Health Diet is not grounded in environmental science at all — a fact even confirmed in the report’s own glossary.He also highlights a key finding from the UN’s FAO: shifting to plant-based diets was ranked among the least effective ways to reduce livestock-related emissions, far behind solutions like improving animal health and increasing productivity.📌 Key topics covered:Why the “Planetary Health Diet” isn’t actually about planetary healthWhat the data really says about livestock’s role in climate changeThe misplaced focus on animal agriculture vs. major carbon emittersConflicts of interest and misleading media narrativesProven methane reduction strategies already working in CaliforniaWhy plant-based diets are impractical to scale — and minimally effective for emissions💡 If you’ve ever wondered whether giving up animal foods is the answer to climate change, or if the environmental case against meat holds up to scientific scrutiny, this interview is a must-watch.👉Subscribe to Metabolic Mind for more of the latest news and research regarding metabolic health, neurological health, and proven dietary interventions: https://www.youtube.com/@metabolicmind.#MetabolicMind #FoodAsMedicine #PlanetaryHealthDietExpert Featured:Frank M Mitloehnerhttps://twitter.com/GHGGuruhttps://clear.ucdavis.edu/people/frank-mitloehnerhttps://clear.ucdavis.edu/https://www.youtube.com/@clearcenteratucdavishttps://www.instagram.com/ghgguru/Resources Mentioned:The Eat-Lancet Planetary Health Diethttps://eatforum.org/eat-lancet/the-planetary-health-diet/FAO Pathways Towards Lower Emissionshttps://openknowledge.fao.org/server/api/core/bitstreams/a06a30d3-6e9d-4e9c-b4b7-29a6cc307208/contentCommon Ground Filmhttps://commongroundfilm.org/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

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