28ish Days Later

Day Three: Pain And Prejudice

Mar 21, 2022
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INSIGHT

Prostaglandins Drive Period Pain

  • Prostaglandins rise around menstruation and drive both uterine contractions and inflammation.
  • That inflammation and smooth-muscle contraction explain cramps and sometimes diarrhea during periods.
ADVICE

Use Anti-Inflammatories Early

  • Use anti-inflammatories like ibuprofen to manage many cases of menstrual pain.
  • These drugs reduce prostaglandin-driven inflammation and can make cramps more bearable.
ANECDOTE

Sixteen Years Of Debilitating Pain

  • Phoebe endured debilitating pelvic cramps for 16 years, often vomiting and losing sleep.
  • She describes worsening intensity and long recovery that shredded her ability to cope mentally.
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