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Quick takeaways
- When diagnosing male hypogonadism, clinical symptoms and biochemical evidence of low testosterone should be considered, along with variations in testosterone receptor sensitivity and other medical conditions.
- The prevalence of male hypogonadism is estimated to be between 6 to 12%, and diagnosing the condition requires evaluating clinical signs, confirming low testosterone levels through specific lab tests, and considering the sensitivity of individuals to androgens.
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Main Ideas
Male hypogonadism is a clinical syndrome resulting from low testosterone levels. Testosterone levels can vary throughout the day and should be measured between 8 a.m. to 10 a.m. in a fasted state. There are various forms of testosterone that can be measured, including total testosterone, free testosterone, and bioavailable testosterone. It is important to consider both clinical symptoms and biochemical evidence of low testosterone when diagnosing male hypogonadism. The interpretation of testosterone levels should also take into account the impact on physical health and well-being. Repeat testing may be necessary to confirm low testosterone levels, and the cutoff for low testosterone varies among different societies. Other medical conditions and variations in testosterone receptor sensitivity should be considered when evaluating low testosterone levels.
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