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Episode #228: Testosterone Replacement Therapy
Barbell Medicine Podcast
The Risks of Acquired Hypogonitism
There's a lack of large systematic studies, though, really about like thoroughly evaluating risk factors and sort of like the risk potential. Sickle cell anemia is cited as a known cause of hypogonitism, but it's only reported in different case series. So maybe that's the problem. In any case, it's just not been thoroughly investigated enough with the rigor that you would expect considering how confidently people feel about testosterone replacement therapy on the internet.
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