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Episode #228: Testosterone Replacement Therapy
Barbell Medicine Podcast
The Role of Testosterone in Hormone Signaling
Testosterone itself as produced by the lidig cells of the testes has a negative feedback at multiple levels. If testosterone levels are low, the hypothalamus and the pituitary gland both get signaled like not enough T in the system. And so we will interpret a low testosterone measurement differently depending on whether FSH and LH levels are high or if they are normal or low. Those lead us in two different directions of trying to kind of localize where the problem is.
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