AI Snips
Chapters
Transcript
Episode notes
Infant C. diff Paradox
- Babies can get C. diff colitis, but they seem protected compared to adults.
- Babies have high colonization rates but exceedingly rare C. diff infections.
C. diff Discovery
- In 1935, O'Toole and Hall isolated C. diff from asymptomatic newborns.
- Guinea pigs inoculated with the bacteria developed severe colitis, highlighting its pathogenic nature.
C. diff's Rise
- C. diff's significance as a pathogen has dramatically increased in the last 20 years.
- It was not initially recognized as a major concern even in recent medical history.