Siim Land Podcast

#444 The Best Bloodwork for Longevity - Dr Michael Lustgarten

Mar 14, 2025
Dr. Michael Lustgarten, an expert in bloodwork analysis, reveals how tracking crucial blood markers can extend longevity. He discusses the importance of understanding biomarkers beyond just cholesterol and glucose, and their relationship with chronic diseases. Lustgarten emphasizes the risks of low cholesterol in older adults and calls for meticulous health tracking. He also shares insights on the impact of protein safety and the significance of monitoring health metrics to improve well-being over time.
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INSIGHT

Blood Cells as Longevity Markers

  • Prioritize blood markers by blood cell types due to their blood volume proportion and longevity relevance.
  • Red blood cell markers like MCV and RDW are underrated yet crucial for longevity tracking.
INSIGHT

Focus on Major Blood Proteins

  • Focus on high-concentration proteins like albumin, globulins, and fibrinogen in blood analysis.
  • Low abundance proteins like cytokines are important but should complement, not dominate, biomarker tracking.
ADVICE

Basic Annual Bloodwork Tests

  • Get a standard chemistry panel and complete blood count at least annually.
  • Add HSCRP and testosterone for a broader view of inflammation and hormonal aging.
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