How Shift Workers Can Use Light, Melatonin, Naps, Physical Activity, and Nutrition to Feel Better | Debra Skene, Professor of Neuroendocrinology
Nov 15, 2023
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Debra Skene, Professor of Neuroendocrinology, discusses the effects of light, melatonin, naps, physical activity, and nutrition on shift workers' wellbeing. They delve into the role of light exposure in our internal clocks, the impact of melatonin on circadian systems, and the benefits of time-restricted eating. The podcast also reflects on the influential work of Josephina Ren in chronobiology.
Light exposure in the morning advances the circadian timing system, while light in the evening delays it.
Melatonin can be used to shift the master clock, but combining it with light exposure negates its effects.
Time-restricted eating, limiting calorie consumption to a 12-hour window or less each day, may benefit shift workers.
Deep dives
The influence of light exposure on circadian clocks
Light exposure acts as the main time cue for the master clock in the brain, influencing sleep-wake cycles. The phase response curve illustrates how the direction of the master clock changes based on the timing of light exposure relative to the body's clock. Light in the morning advances the circadian timing system, while light in the evening delays it.
The role of melatonin in sleep and clock regulation
Melatonin is an internal signal of darkness, indicating the time to sleep. It can be used to shift the master clock and has both acute and long-term effects. Ingesting melatonin in the morning delays the clock, while taking it in the evening advances it. However, combining melatonin with light exposure cancels out its effects.
The importance of high-intensity, blue-contained light during the day
To stay entrained to the natural light-dark cycle, it is recommended to have high-intensity, blue-contained light during the day. This light helps wake up, stay alert, operate efficiently, and maintain synchronization with the natural environment. Before sleep, the intensity and wavelength of light should be toned down to prepare the body for rest.
The need for cautious melatonin use in children
While melatonin is generally considered safe, its use in children requires caution. Prescribing melatonin should be based on each child's specific needs and condition. The safety and long-term effects of melatonin in pediatric populations need further research.
The potential benefits of time-restricted eating for shift workers
Time-restricted eating, limiting calorie consumption to a 12-hour window or less each day, might be beneficial for shift workers. Eating only during daylight hours and avoiding eating between midnight and morning could help align meal timing with the master clock's rhythm and improve metabolic health. Further studies are needed to determine optimal timing and dietary composition for shift workers.
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