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Core Mechanisms Of ADHD
- ADHD is primarily a disorder of executive dysfunction involving inhibition, reward sensitivity, and impulsivity.
- These three mechanisms together explain common ADHD symptoms like poor focus and intolerance of delayed gratification.
Why ADHD Raises Addiction Risk
- The ADHD brain's deficits in inhibition and altered reward sensitivity increase vulnerability to substance use.
- Those impaired protections make it much easier for people with ADHD to start and keep using substances.
Brain Regions And Dopamine In ADHD
- Key brain regions involved are the prefrontal cortex, anterior cingulate, and striatum with dopamine dysfunction.
- ADHD shows reduced anterior cingulate activity and impaired dopamine across these regions.


