The Problem With...

The Problem With Aging - Andrew Steele (4k)

Dec 16, 2025
Andrew Steele, a scientist and co-founder of the Longevity Institute, dives into the complexities of aging and longevity. He discusses how aging is the leading cause of death in wealthy nations, attributing 90% of fatalities to this factor. Andrew debunks myths surrounding 'anti-aging' and criticizes misleading influencer claims. He highlights how lifestyle choices, rather than just genetics, shape our life expectancy. The conversation also touches on promising treatments like GLP-1 drugs and the ethical implications of extending human life.
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INSIGHT

Aging Drives Most Diseases

  • Aging is the single biggest risk factor for most major diseases and causes ~90% of deaths in rich countries.
  • Treating aging as a common biological process could prevent many diseases at once.
INSIGHT

Your Face Reflects Biological Age

  • Perceived facial age correlates with biological age and predicts disease and mortality risk.
  • Epigenetic clocks and blood tests are useful research tools but not yet reliable consumer products.
INSIGHT

Genes Aren't Destiny

  • Genetics explain only about 5–25% of longevity, leaving 75–95% to lifestyle and luck.
  • That means much of lifespan remains modifiable despite genetic luck.
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