Psychiatry & Psychotherapy Podcast

Creatine and Mental Health

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Apr 18, 2025
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INSIGHT

Creatine Enhances CBT Effectiveness

  • Creatine improves outcomes when added to cognitive behavioral therapy for depression.
  • Standard 5 grams daily dose may be insufficient, with higher doses showing greater brain creatine increase.
INSIGHT

Higher Creatine Doses Boost Brain Levels

  • Brain creatine levels increase more with higher supplementation doses.
  • Ten grams daily nearly doubles frontal lobe creatine versus lower doses, suggesting dose-dependent brain effects.
ADVICE

Creatine Intake Tips

  • Take creatine with plenty of water and food to reduce gastrointestinal discomfort.
  • Dissolve powder well and eat a small snack like peanut butter for better tolerance.
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