The Jesse Chappus Show 668: This Stops Insulin Resistance in Its Tracks | Dr. Roshani Sanghani
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Sep 2, 2025 Dr. Roshani Sanghani, a board-certified endocrinologist and metabolic health practitioner, shares her expertise on insulin resistance and hormone optimization. Listeners learn about the importance of proactive health screenings, especially for those of Indian descent. She emphasizes lifestyle changes, like time-restricted eating and low-carb diets, to combat insulin resistance. The discussion also covers the impact of chronic stress, the role of strength training in diabetes management, and the nuances of vegetarian dietary practices for metabolic health.
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Metabolic Disease Often Has No Symptoms
- Most people with metabolic ill health feel fine and lack obvious symptoms, so screening is essential.
- Check fasting glucose, fasting insulin, A1c, lipids, liver tests and uric acid to catch early insulin resistance.
Why Insulin Levels Rise Early
- Insulin rises because cells stop responding, not because insulin itself is faulty.
- The body raises insulin to preserve normal glucose as insulin effectiveness declines.
Liver Is A Glucose Provider, Not A Fat Depot
- The liver provides glucose via gluconeogenesis and is vulnerable to fructose-driven fat accumulation.
- Fatty liver arises from high insulin plus high fructose and can progress even with small fat deposits.
