#415 Longevity Doctor Shares Regeneration Protocol - Alexis Ortega MD
Aug 24, 2024
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Dr. Alexis Ortega, a longevity expert and regenerative medicine specialist, discusses innovative strategies to enhance lifespan and healthspan. He outlines a three-step process for longevity that focuses on detoxification, regeneration, and personalized health. Topics include the effects of senolytics on aging cells, the role of exosomes in regenerative medicine, and the importance of restoring melatonin levels. Alexis also shares his insights on effective supplements, lifestyle adjustments, and the mystery behind achieving a lifespan beyond 120 years.
Comprehensive health assessments, including biological ages and immune function, are crucial for tailoring longevity interventions effectively.
Detoxification is essential before regenerative therapies to eliminate harmful substances, enabling better healing and regeneration processes.
Utilizing peptides and lifestyle changes alongside supplements significantly enhances cellular health and supports longevity, especially in older adults.
Deep dives
The Importance of Measuring Health Metrics
Measuring various health metrics is crucial for understanding one’s health status and making informed decisions regarding longevity. A thorough assessment includes evaluating biological ages, NAD levels, immune function, and even toxic heavy metals through different tests. This comprehensive data helps tailor interventions to individual needs, addressing any underlying issues. For instance, identifying a discrepancy between chronological age and epigenetic or vascular age can prioritize treatment plans effectively.
Detoxification as a Precursor to Regeneration
Before initiating any regenerative therapies, it is essential to remove harmful substances from the body, a process known as detoxification. This phase involves eliminating toxins, heavy metals, and senescent cells, which could otherwise impair the regeneration process. Various methods are employed, including intravenous senolytics, glutathione therapies, and chelation for heavy metals. By detoxifying first, the body is prepared to heal, regenerate, and respond better to subsequent treatments.
Advancements in Regenerative Therapies
Regenerative therapies are becoming more sophisticated, focusing on employing natural body processes to repair and rejuvenate tissues. This includes the use of intravenously administered NAD to restore levels more quickly and utilizing exosomes derived from stem cells to promote healing across various tissue types. Exosomes act as signaling molecules that can enhance cell communication, leading to improved recovery and function. The potential of mesenchymal stem cell exosomes, in particular, showcases promising results in treating chronic conditions and addressing age-related ailments.
The Role of Peptide Therapy and Supplements
Peptides and specific supplements play a vital part in rejuvenation protocols, aimed at enhancing cellular health and longevity. For instance, peptides like epithelon are used to regenerate telomeres, while supplements like NMN and alpha-ketoglutarate help support NAD levels and stabilize the epigenome. Regularly assessed supplementation can bolster both physical performance and cognitive function, as well as regulate the metabolism of essential nutrients. Tailoring these interventions based on individual health assessments ensures they are both effective and safe.
Lifestyle Adjustments for Longevity
Implementing sustainable lifestyle changes is essential for enhancing one’s longevity alongside medical interventions. This includes focusing on strength training and proper nutrition to maintain muscle mass and metabolic health, alongside potentially easing intermittent fasting practices. Recommendations shift based on individual circumstances, particularly for older adults who benefit from frequent smaller meals high in protein. Adopting a balance between calorically rich periods and fasting can optimize health outcomes while minimizing risks associated with aging.