The Joe Cohen Show The Science of Methylation and MTHFR with Dr. Ben Lynch
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Mar 8, 2024 Dr. Ben Lynch discusses methylation pathways, homocysteine, and personalized supplement recommendations. They explore the role of B vitamins, epigenetics, and alternative tests. Topics include nitrous oxide exposure, folate metabolism, histidine supplementation, and optimizing health with data-driven decisions.
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Methylfolate Side Effects Story
- Ben Lynch shared a personal story of getting headaches and irritability from taking high doses of methylfolate daily.
- He realized that simply having the MTHFR genetic variation doesn't mean you should blindly supplement with methylfolate.
Evolutionary Role of MTHFR Variants
- MTHFR variations may have been evolutionarily beneficial by conserving upstream folates for red and white blood cell production.
- This conservation helps individuals survive conditions like malaria by supporting blood cell regeneration and DNA synthesis.
Protect and Support MTHFR Enzyme
- Reduce the workload for your MTHFR enzyme to support it better.
- Avoid exposure to nitrous oxide like laughing gas to prevent impairing methylation pathways.