Platform Trials: A New Approach in Clinical Research

Platform trials have introduced a shift in traditional clinical research methodologies by focusing on efficiency and adaptability. These trials allow for flexibility in sample sizes and the incorporation of new interventions without the need for fixed numbers. Educating institutional review boards and ethics committees on the continuous nature of platform trials is crucial to ensure proper oversight. The use of a core protocol supplemented by specific intervention documents aids in this process, ensuring transparency and review of new therapies.