Navigating Challenges in Platform Trials: Education, Funding, and Statistical Designs

The chapter delves into the challenges faced in educating institutional review boards about platform trials, emphasizing continuous education over persuasion. It also addresses funding sustainability by exploring potential funding models and discussing the perspectives of research funders. Statistical designs in platform trials, including the shift from fixed sample sizes to Bayesian designs, are discussed, highlighting the importance of global collaboration and efficient evaluation methods.