The Energy Blueprint Podcast Dr. Gabrielle Lyon: Forever Strong Playbook and Muscle-Centric Medicine
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Jan 31, 2026 
Dr. Gabrielle Lyon, a Fellowship-trained physician and muscle-centric medicine pioneer, argues that being undermuscled—not overfat—is the core health problem. She explores muscle as an endocrine organ, intermuscular fat’s role in metabolic disease and PCOS, elevated protein needs in new guidelines, myokines’ systemic effects, and practical strategies from her Forever Strong Playbook.
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Undermuscled Not Overfat
- Obesity may be a symptom, not the root problem; unhealthy skeletal muscle is the primary issue.
- Gabrielle Lyon argues most people are undermuscled and muscle health drives metabolic disease risk.
Muscle Is An Endocrine Organ
- Skeletal muscle is an endocrine organ that secretes myokines affecting the brain, liver, pancreas and immunity.
- Muscle contraction and training transform systemic health beyond strength or appearance.
Shift Focus From Fat Loss To Muscle Gain
- Reframing health from body-fat loss to muscle gain shifts control to voluntary actions like resistance training.
- Lyon says focusing on muscle is empowering because muscle is within our control.
