LONGEVITY with Nathalie Niddam cover image

LONGEVITY with Nathalie Niddam

Episode #263: Dr. Greg Kelly: NAD+ in Aging: Effects on Longevity + How it Works

Aug 30, 2024
Dr. Greg Kelly, a leading expert and author focused on NAD+ and aging, shares fascinating insights into the role of this vital molecule in longevity. He explains how NAD+ supports cellular health and its crucial role in energy production and DNA repair. The discussion includes the timing of NAD+ supplementation for optimal metabolic benefits and explores the effectiveness of NAD+ infusions. Additionally, Dr. Kelly highlights the relationship between NAD+ levels and gut health, emphasizing the importance of a balanced approach to supplementation.
01:26:04

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • NAD+ plays a crucial role in cellular energy production and longevity, but its levels decline with age, necessitating supplementation.
  • Supplementing with NAD+ precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) can enhance cellular resilience and recovery.

Deep dives

Understanding NAD and Its Role in Longevity

NAD, or nicotinamide adenine dinucleotide, plays a critical role in cellular energy production and longevity. This molecule shifts between oxidized and reduced states, functioning as a redox agent essential for generating ATP, the energy currency of cells. As people age, NAD+ levels decline, which is associated with various age-related conditions. This decline emphasizes the importance of supplementing with NAD precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) to support cellular health and resilience.

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