LONGEVITY with Nathalie Niddam

Episode #263: Dr. Greg Kelly: NAD+ in Aging: Effects on Longevity + How it Works

Aug 30, 2024

Dr. Greg Kelly, a leading expert and author focused on NAD+ and aging, shares fascinating insights into the role of this vital molecule in longevity. He explains how NAD+ supports cellular health and its crucial role in energy production and DNA repair. The discussion includes the timing of NAD+ supplementation for optimal metabolic benefits and explores the effectiveness of NAD+ infusions. Additionally, Dr. Kelly highlights the relationship between NAD+ levels and gut health, emphasizing the importance of a balanced approach to supplementation.

01:26:04

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Episode guests

Greg Kelly

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Quick takeaways

NAD+ plays a crucial role in cellular energy production and longevity, but its levels decline with age, necessitating supplementation.

Supplementing with NAD+ precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) can enhance cellular resilience and recovery.

The timing of NAD precursor supplementation might be essential, as aligning it with the body's circadian rhythm can optimize its effectiveness.

Deep dives

Understanding NAD and Its Role in Longevity

NAD, or nicotinamide adenine dinucleotide, plays a critical role in cellular energy production and longevity. This molecule shifts between oxidized and reduced states, functioning as a redox agent essential for generating ATP, the energy currency of cells. As people age, NAD+ levels decline, which is associated with various age-related conditions. This decline emphasizes the importance of supplementing with NAD precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) to support cellular health and resilience.

Intro

4min

The Power of NAD in Aging

4min

Understanding NAD: From History to Health

8min

The Role of NAD+ in Longevity and Cellular Repair Mechanisms

4min

NAD+ Precursors: NMN and NR Insights

20min

The Impact of Timing on NAD+ Supplementation and Metabolic Health

5min

Exploring NAD Testing and Infusion Effects

4min

The Complexities of Mineral Supplementation and NAD+ Infusions

3min

The Vital Role of NAD+ in Cellular Health

12min

10.

Understanding NAD+ Optimization and Cellular Health

4min

11.

Understanding the NAD+ Salvage Pathway and Enzyme Activity

2min

12.

Examining NAD+ Levels and Metabolomic Changes in Aging

5min

13.

Energizing Health: The NAD+ Impact

9min

14.

Emphasizing Foundations and Enhancements for Longevity

3min

Have you ever wondered why some people seem to age more gracefully than others? The answer might lie in a molecule called NAD+. In this podcast episode, we dive deep into the world of NAD+ with Dr. Greg Kelly, a leading expert in the field.

We discuss a comprehensive overview of NAD+, its role in longevity and cellular resilience, and the importance of timing when supplementing it. We also dive into the effectiveness of NAD+ infusions, the importance of NAD+ resources in cellular response to stress, and Qualia Life’s NAD+ supplement.

Gregory Kelly is Director of Product Development at Neurohacker Collective, a naturopathic physician (N.D.), and the author of the book Shape Shift. He was the editor of the journal Alternative Medicine Review and has been an instructor at the University of Bridgeport in the College of Naturopathic Medicine, where he taught classes in Advanced Clinical Nutrition, Counseling Skills, and Doctor-Patient Relationships. Dr. Kelly has published hundreds of articles on natural medicine and nutrition contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed.

Want to try Qualia NAD+? Visit http://www.qualialife.com/longevity and use code LONGEVITY for 15% off your order.

Thank you to our sponsors for making this episode possible:

Stemregen: Save 15% on your first order at http://www.stemregen.co/nat, use code NAT15

Mitopure: Use code NAT10 for 10% your order at https://www.timelinenutrition.com/shop/nutrition

BEAM Minerals: Go to https://www.beamminerals.com and use code NAT20 to get 20% off your order

Find more from Dr. Greg Kelly:

Website: https://www.qualialife.com/people/greg-kelly

Instagram: @qualialife

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Join Nat’s Membership Community: https://www.natniddam.com/bsp-community

Instagram: https://www.instagram.com/nathalieniddam/

Website: www.NatNiddam.com

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

What We Discuss:

03:01 The History and Origins of NAD+

10:12 NR vs. NMN: Comparing NAD+ Precursors

15:03 The Importance of Timing in NAD+ Supplementation

24:57 Exploring NAD+ Infusions: Benefits and Risks

37:50 The Effectiveness of NAD+ Infusions

45:21 NAD's Role in Longevity and Cellular Resilience

51:46 The Importance of NAD+ Resources in Cellular Response to Stress

56:23 The Salvage Pathway and ATP Production

01:04:25 Quality of Life's NAD+ Supplement: Supporting NAD+ Levels and ATP Production

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LONGEVITY with Nathalie Niddam

Episode #263: Dr. Greg Kelly: NAD+ in Aging: Effects on Longevity + How it Works

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

Deep dives

Understanding NAD and Its Role in Longevity

The Process of NAD Synthesis

The Impact of NAD on Cellular Stress and Recovery

The Debate: NMN vs. NR as Effective Supplements

The Importance of Timing and Synergy in NAD Supplementation

Remember Everything You Learn from Podcasts