127 – All About Aging with Richard Acton

1

Introduction

00:00 • 2min

2

The Bayesian Conspiracy: Inyash Brodsky

02:16 • 2min

3

How to Be a Bioinformatics Researcher

03:52 • 4min

4

How to Read a Sci-Fi Story

07:38 • 2min

5

The Less Wrong Posts

09:19 • 2min

6

Petrov Day: A Post-Nuclear War World

11:18 • 2min

7

How to Convince Me That Two Plus Two Equals Three

13:23 • 2min

8

The Evidence That Convinces Me That Two Plus Two Equals Four

15:10 • 2min

9

The Secret Number

16:55 • 3min

10

The Secret Name of God

19:44 • 2min

11

The Importance of Organizing Thoughts

21:50 • 2min

12

The Importance of Pre-Registration in Scientific Research

23:58 • 3min

13

The Challenge of Reproducibility in Bioinformatics

26:31 • 2min

14

How to Describe Your Effectiveness as a Rationalist

28:48 • 2min

15

The Importance of Optimizing for Survival

30:26 • 2min

16

Evolution and the Evolution of Life

32:29 • 3min

17

Tesla's Self-Driving Cars

35:19 • 2min

18

The Importance of Writing Your Bottom Line

36:58 • 3min

19

The Differences Between Crown Cross-Fusion and the American Approach

39:59 • 2min

20

The Epigenetics of Aging

41:42 • 2min

21

The Origins of Epigenetics

43:44 • 4min

22

The Dangers of the FDA's Littomide

47:36 • 2min

23

The Conservative Approach to Safety Assessments for Drugs for Pregnant Women

49:31 • 3min

24

The Epigenetic Information Theory of Aging

52:08 • 3min

25

The Epigenetic Aging Hypothesis

55:02 • 2min

26

The Role of the Yamunaka Factors in Regenerative Medicine

57:12 • 2min

27

How to Inject a Gene Into a Cell

59:35 • 3min

28

How to Eliminate Senescent Cells Permanently

01:02:14 • 4min

29

The Paradox of Mouse Lifespan

01:06:29 • 2min

30

The Safety of Genetic Engineering in Humans

01:08:25 • 2min

31

The Evolution of Senescent Cells

01:10:31 • 3min

32

The Importance of Restoring Genome Information

01:13:53 • 2min

33

The Role of Genetic Damage in Aging

01:16:20 • 5min

34

The Selection Shadow in Evolution

01:21:44 • 2min

35

The Evolution of Longevity

01:23:23 • 2min

36

The Future of Longevity Interventions

01:25:02 • 2min

37

Sonolytics and Longevity Interventions

01:27:14 • 3min

38

The Side Effects of Rapamycin

01:30:06 • 3min

39

How to Predict How Old You Are

01:33:18 • 2min

40

How to Predict Methylation in a Genome

01:35:36 • 2min

41

The Role of Methylation in Longevity

01:37:15 • 4min

42

How to Get a Methylization Test

01:40:58 • 2min

43

The Cost of DNA Methylation Tests

01:42:56 • 2min

44

The Future of Aging Biology

01:44:45 • 3min

45

How to Get Started in a Niche Area

01:47:52 • 2min

46

The Importance of Software in the Internet of Things

01:49:25 • 4min

47

The Importance of Rationality in Reading

01:53:22 • 2min