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Gene Smith on polygenic screening; gene editing to give our children the happiest, healthiest, best lives they can live; and if we can do this in adults as well. Plus how this will interface with the AI future.   LINKS How To Make Super Babies How to have Polygenically Screened Children Significantly Enhancing Adult Intelligence With Gene Editing May Be Possible Meiosis is all you need Welcome Polygenically Screened Babies Gwern on Embryo Selection Being Ladylike for Autistic Women Bayes Blast Dear Grom and Other Stories  Want to run an HPMOR Anniversary Party, or get notified if one’s happening near you? Fill this out! 00:00:05 – Super babies! 01:35:34 – HPMOR 10 year anniversary! 01:37:51 – Guild of the Rose 01:39:05 – Steven’s follow-up on Being Ladylike for Autistic Women 01:46:10 – Thank the Supporter! Our Patreon, or if you prefer Our SubStack Hey look, we have a discord! What could possibly go wrong? We now partner with The Guild of the Rose, check them out. Rationality: From AI to Zombies, The Podcast LessWrong Sequence Posts Discussed in this Episode: none Next Sequence Posts: Decoherence The So-Called Heisenberg Uncertainty Principle

Eneasz tells Jen about Sympathetic Opposition’s How and Why to be Ladylike (For Women with Autism), and the podcast takes a 1-episode break

Jacob Falkovich on finding a good match and selfless dating LINKS SecondPerson.Dating – why dating sucks and how you will unsuck it Jacob’s post on soccer player skill distribution Go Fuck Someone Selfless Dating Consensual Hostility (re consent culture) steelmanning Monogamy A recent(ish) TBC episode on polyamory Eneasz on finding partners that like the opposite sex Dear Grom and Other Stories 00:00:05 – Dating 01:04:56 – Guild of the Rose 01:08:22 – Less Wrong Posts 01:19:35 – Thank the Supporter! Our Patreon, or if you prefer Our SubStack Hey look, we have a discord! What could possibly go wrong? We now partner with The Guild of the Rose, check them out. Rationality: From AI to Zombies, The Podcast LessWrong Sequence Posts Discussed in this Episode: Zombies: The Movie Three Dialogues on Identity Next Sequence Posts: none

Dive into the wild world of shitcoins and their connection to a political figure. Discover the thrilling and risky nature of investing in these volatile assets through personal stories. Reflect on the GameStop short squeeze and the insights from the film 'Dumb Money'. The conversation highlights the dangers of speculative investments and promotes a cautious approach to the crypto market.

Dive into the ethical maze of sacrificing a pet to save a friend’s life. The discussion illuminates troubling moral dilemmas around trust and desperate pacts. Explore the implications of promises made in dire circumstances, and how they reflect on friendships. Plus, a lively Q&A that challenges listeners' perspectives on this heavy topic. It’s a conversation that mixes dark humor with deep philosophical inquiry, leaving you to ponder what you would do in a similar situation.

Eric discusses integrating our emotions via observation and adjustment. His free course is at EnjoyExisting.org or email him – eric@ericlanigan.com LINKS EnjoyExisting.org Ugh Fields You Have Two Brains – Eneasz spends more words on this emotion-brain speculation at this blog LessWrong/Lighthaven Donations – you have until Jan 13! 00:00:05 – Integrating Emotions 01:02:30 – Guild of the Rose 01:05:31 – Less Wrong Posts 01:24:38 – Thank the Supporter! Our Patreon, or if you prefer Our SubStack Hey look, we have a discord! What could possibly go wrong? We now partner with The Guild of the Rose, check them out. Rationality: From AI to Zombies, The Podcast LessWrong Sequence Posts Discussed in this Episode: No Individual Particles Identity Isn’t In Specific Atoms Next Sequence Posts: Zombies: The Movie Three Dialogues on Identity

If you haven’t yet, go fill out the 2024 LW Census. Right here.

Oliver Habryka, a key figure in the rationalist community, discusses the intriguing evolution of LightHaven from the LessWrong platform. He explores the impact of the FTX collapse on funding and community dynamics. Habryka shares insights on innovative conference structures and the ethical implications of organizations like Leverage Research. The conversation touches on the importance of community engagement, donor recognition, and plans for nurturing intellectual exchange at LightHaven. Join the journey through rationality, empathy, and the future of effective altruism!

We talk to Zoe Isabel Senon about longevity, recent advances, longevity popup cities & group houses, and more (not necessarily in that order). Spoiler: Eneasz is gonna die. Also we learn about Network States! LINKS Vitalist Bay Aevitas House – remember that for these Zoe it helps if you mention you listen to The Bayesian Conspiracy as examples of alignment Vitalia City Lighthaven Fundraiser (direct donation link here) Scott Alexander’s response to Illusion of Moral Decline US crime rates over the last 50 years 00:00:05 – Zoe, Longevity, Community 01:03:49 – Is Eneasz gonna die? 01:12:19 – What the heck is a network state? 01:31:01 – Lighthaven fundraiser 01:33:17 – Guild of the Rose 01:34:20 – Feedback 01:44:50 – Thank the Supporter! Our Patreon, or if you prefer Our SubStack Hey look, we have a discord! What could possibly go wrong? We now partner with The Guild of the Rose, check them out. Rationality: From AI to Zombies, The Podcast LessWrong Sequence Posts Discussed in this Episode: none Next Sequence Posts: No Individual Particles Identity Isn’t In Specific Atoms