The Kevin Rose Show David Sinclair, Ph.D., Why We Age and Why We Don't Have To (#33)
Oct 30, 2019
David Sinclair, Ph.D., a Harvard professor renowned for his pioneering research on aging, dives into fascinating insights about longevity. He discusses breakthrough treatments and the importance of compounds like resveratrol in combating age-related decline. The conversation touches on the revolutionary role of NAD boosters and gene editing in extending lifespan. Sinclair also emphasizes how lifestyle choices impact aging and the potential of advanced technologies for personalized health monitoring—both for humans and pets. Get ready to rethink aging!
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Resveratrol Discovery
- David Sinclair discovered resveratrol, a compound in red wine, could activate SIRT1, a gene linked to longevity.
- This discovery happened at home with a newborn and a microscope in his dining room.
Information Theory of Aging
- Aging is a loss of information, both genetic and epigenetic.
- The epigenome, which reads genes, malfunctions over time like a scratched DVD.
Analog Epigenome
- Epigenetic information is stored in analog format, making it fragile and susceptible to damage.
- DNA damage, especially broken chromosomes, disrupts the epigenome's ability to read genes correctly.
