REBEL Cast REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension
May 18, 2023
Chapters
Transcript
Episode notes
1 2 3 4 5 6 7
Introduction
00:00 • 3min
Clovers for Sepsis-Induced Hypotension
03:24 • 5min
The Effects of Volume Overload on Resuscitation Therapy
08:13 • 3min
The Effects of Resuscitation on Vasopressor Use
10:48 • 4min
The Heterogeneity of Sepsis Trials
14:40 • 2min
The Importance of Clinical Gestalt in the Treatment of Sepsis
16:50 • 2min
The Safety of Restrictive Fluids in Sepsis-Induced Hypotension
18:53 • 2min
Background: IV fluids are part of the standard resuscitation bundle in septic shock, however it is unclear if they provide a significant benefit. These patients can have a vasodilated vascular bed and the initial use of fluids is hypothesized to serve two purposes: Augmenting the macrovascular system (stroke volume and cardiac output) and augmenting the ...