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#47 – A Nefarious Orchestra: Gram-Negative Resistance Mechanisms Part 2
Oct 29, 2021
00:00
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- Understanding ESBL evolution is crucial for effective treatment strategies.
- Tailored approaches are needed due to differences in AmpC enzymes among bacterial species.
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ESBLs and ESBL: Characteristics and Development
ESBLs represent a significant challenge in gram-negative pathogens, particularly surrounding enzymes like ESBLs, which hydrolize beta-lactam antibiotics. These enzymes, such as ESBLs, are associated with altered target binding and mutations, affecting susceptibility to antibiotics. Understanding the evolution and mechanisms of ESBLs is crucial for effective treatment.
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