The Glycene for Asyrian Substitution in the H Ten Helix

i want to be a bit selfish for a second here and ask if you can kind of describe what those ameno acid substitutions do to the confirmational changes of the enzyme that really change the substraight profile. You mention the glycene for asyrian substitution at position two, 30, eightd two, forty andand i apologize fo this, but i want to be selfish for asecond here and askIf you could tell us about the active sights in the omega loop and the b three beta strand in the h ten helix. What's really happening at the ensomatic level that's changing the structure of that ensign well, i was very fortunate to have a friendship