Is the Oxa Ensine a Sufflo?

Some oxes now are found with metallos. And i'd like to refer those as the evil twins. Aes, you know, searing carb penemes activity and this metallo corb penames activity. How do we bipass these sorts of mechanisms? There are opportunities around that. We can't discuss every drug that's been made but there are opportunities for medicinal chemist to bipass that.