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CPP And MAP Interact Dynamically
- CPP and MAP are not independent; changing MAP can alter ICP through vascular responses.
- Increasing MAP can lower ICP by improving cerebral autoregulation rather than always raising ICP.
Successful MAP Increase Example
- In a case the team increased noradrenaline from 17 to 23 and MAP rose from 80 to 87.
- ICP fell from 21 to 18 over 30 minutes, improving bedside comfort.
How To Run A MAP Challenge Safely
- Perform a MAP challenge under direct clinician supervision with no other interventions.
- Increase vasopressors, observe ICP response, and adjust therapy based on the result.


