The Diary Of A CEO with Steven Bartlett cover image

The Diary Of A CEO with Steven Bartlett

Moment 209: The Real Reason You’re Gaining Weight (Even If You’re Exercising!)

Apr 18, 2025
Join geneticist Giles Yeo, an expert in obesity and eating behavior, as he unveils the science behind weight gain and your metabolism. He explains how genes influence hunger and why your body clings to fat, particularly as you age. Yeo challenges the notion that exercise is a silver bullet for fat loss, discussing its limited effectiveness. He also shares practical strategies for sustainable weight management that go beyond common misconceptions, highlighting the importance of resistance training and understanding your body's natural 'set point'.
18:07

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Genetic factors significantly influence an individual's propensity for weight gain, indicating that biology plays a crucial role in dieting success.
  • Maintaining muscle mass through resistance training is essential for healthy aging and managing weight, especially as metabolism changes with age.

Deep dives

Genetic Influences on Eating and Disease Risk

Genetic factors play a significant role in how individuals respond to food, eating habits, and their risk of obesity and related diseases. For instance, it has been observed that people from certain ethnic backgrounds, such as South Asians and East Asians, are more susceptible to type 2 diabetes at lower body mass indices compared to other groups, highlighting the interplay between genetics and cultural dietary habits. The discussion also points to specific genes, such as the leptin gene, which regulates hunger signals from the brain, and the MC4R gene, mutations of which can predispose individuals to obesity. These genetic predispositions contribute to varying degrees of difficulty for individuals in maintaining or losing weight, suggesting that biology plays a crucial role in dietary behaviors.

Remember Everything You Learn from Podcasts

Save insights instantly, chat with episodes, and build lasting knowledge - all powered by AI.
App store bannerPlay store banner