Core IM | Internal Medicine Podcast

#124 A1c & Glucose Measurements: Mind the Gap Segment

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Apr 26, 2023
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INSIGHT

Glucose Measurement Challenges

  • Measuring glucose is crucial for diabetes diagnosis, but glucose fluctuates greatly.
  • Random, fasting, or glucose tolerance tests each have limitations in capturing the full picture.
INSIGHT

Post-Prandial Hyperglycemia Significance

  • Fasting glucose misses post-prandial hyperglycemia, an early diabetes indicator.
  • Steroids and GLP-1 agonists primarily affect post-prandial glucose, not fasting levels.
INSIGHT

HbA1c: A Long-Term Average

  • Hemoglobin A1c (HbA1c) measures average glucose by assessing glucose bound to hemoglobin over time.
  • It acts as a long-term average, similar to how left atrial size reflects heart health.
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