Core IM | Internal Medicine Podcast

#127 Radiation Oncology Side Effects: 5 Pearls Segment

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May 31, 2023
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INSIGHT

Radiation Fatigue

  • Radiation fatigue's cause is poorly understood, possibly involving cytokine release and inflammation.
  • Fatigue may persist for 6-12 months, peaking at treatment's end and improving gradually.
ADVICE

Fatigue Recovery Timeline

  • Expect fatigue improvement roughly within the same timeframe as the treatment duration.
  • If radiation lasted four weeks, recovery might take a similar period for noticeable changes.
INSIGHT

Cytopenias and Radiation

  • Cytopenias from radiation are generally temporary and resolve with bone marrow regeneration.
  • Don't attribute cytopenias years later to past radiation without excluding other causes like MDS.
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