The HyPaultrophy podcast How MYOPS works with Zan Zupanic
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Jun 3, 2025 Zan Zupanic, a dedicated PhD student in exercise physiology, dives deep into MYOPS and its essential role in training practices. He discusses the nuanced relationship between muscle protein synthesis and hypertrophy, revealing how workout intensity impacts growth. The conversation also highlights the challenges in muscle response research between trained and untrained individuals. Zan sheds light on recovery methods, scrutinizing their effects on muscle adaptation and the critical timing for maximizing protein synthesis. Excitement brews over an upcoming research study, showcasing his academic passion.
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MyoPS Shows Protein Creation Only
- Myofibrillar protein synthesis (MyoPS) rates cannot differentiate between repair and new protein addition.
- Elevated MyoPS indicates muscle protein synthesis but not the specific function of the proteins synthesized.
Volume Extends Anabolic Window
- MyoPS remains elevated longer with more sets; one set returns to baseline around 24 hours.
- Multiple set routines can keep muscles anabolic for up to 72 hours post-exercise.
Protein Synthesis Timing Hypothesis
- Damage repair likely occurs earlier during elevated MyoPS while new protein addition happens later.
- Repairing structural proteins first is logical before adding new contractile units.