
What's Your Problem?
Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better.
iHeartMedia is the exclusive podcast partner of Pushkin Industries.
Latest episodes

May 2, 2024 • 36min
The First Pig to Human Kidney Transplant
Mike Curtis, CEO of eGenesis, discusses genetically engineering pigs for human organ transplants. They explore using CRISPR technology to edit pig genomes, adding human genes for regulatory factors. Ethical considerations and future potential of pig organs in transplants are also highlighted.

Apr 25, 2024 • 38min
Designing a Drone That Delivers
Adam Woodworth, CEO of Wing, discusses the challenges of making drone delivery as common as using a shopping cart. Topics include safety benefits, cost dynamics, noise reduction, drone hook design, operational setup, advancements in drone technology, funding obstacles, and redefining drones as airplanes.

Apr 18, 2024 • 32min
How Do Psychedelics Work?
Gul Dolen, a professor of psychology and neuroscience at UC Berkeley, discusses the common mechanism that psychedelics use to affect the brain, potentially helping those with mental illness and neurological issues like strokes. The podcast explores the intersection of psychedelics and critical periods in brain development, the benefits of combining psychedelics with therapy for stroke recovery, and speculative theories on psychedelics and allergies.

Apr 11, 2024 • 35min
Building Boundary-Breaking Balloons
Kai Marshland, co-founder of WindBorne Systems, discusses building weather balloons for extended flights to improve weather forecasting using AI. The podcast delves into challenges in creating altitude-controlling balloons, data analysis for hurricane forecasts, advancements in AI weather modeling, and the company's mission to revolutionize weather forecasting and climate change mitigation.

Apr 4, 2024 • 39min
Building a Robot That Can Walk the Walk
Jonathan Hurst, a professor at Oregon State University and co-founder of Agility Robotics, discusses designing robots that mimic animal movements for practical use. They explore the challenges of creating robots that can walk like birds and run like animals, testing them in real-world scenarios like warehouses. The podcast highlights the evolution of robot design from academic research to mass production, emphasizing the importance of specialized functionalities in robotics.

Mar 14, 2024 • 36min
Can Your Phone Tell When You're Getting Sick?
The podcast explores how voice patterns can detect health conditions, using AI to analyze acoustic biomarkers. It discusses the potential of smartphones in health detection, the importance of individual nuances in tracking health, and the challenges of balancing privacy with data integrity in AI development.

Mar 7, 2024 • 33min
The High-Stakes Quest to Reinvent Cement
This podcast delves into the challenge of producing carbon-free cement at scale, highlighting the innovative use of electrochemistry to revolutionize the construction industry. It explores the journey of developing a new kind of cement, the environmental impact of traditional cement production, and the drive for technological advancement in reducing carbon emissions.

Feb 29, 2024 • 35min
How a Battery-Powered Stove Could Electrify America
Learn how a battery-powered stove could revolutionize home cooking with high-power demands, induction technology, and grid electricity sales. Dive into challenges of transitioning away from gas stoves and integrating power storage solutions for efficient energy consumption. Explore past projects, failures, and ambitious innovations in this intriguing podcast episode.

Feb 22, 2024 • 36min
3D Printing a Better Rocket
A unique approach to manufacturing rockets using 3D printing, with a vision of sending a rocket and printer to Mars. The podcast explores the challenges and successes of launching rockets, optimizing rocket design, and envisioning a self-sustaining civilization on Mars. Features insights on revolutionizing rocket production, navigating rocket launch challenges, and exploring writing, rocket systems, and Jeff Bezos' patience.

7 snips
Feb 15, 2024 • 40min
Using AI to Help Doctors Save Lives
Suchi Saria, founder and CEO of Bayesian Health, and a professor at Johns Hopkins, discusses using AI to detect hospital patients at risk of complications. Challenges of integrating AI in healthcare, building trust in real-time information, and potential impact on healthcare market. Building an AI model for sepsis detection and the importance of detailed data. Potential impact of software in detecting sepsis and bed sores. Exploring AI applications and user experience. The need for AI to solve people problems.